Results 51 to 60 of about 65,628 (266)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Reemerging Sudan Ebola Virus Disease in Uganda, 2011
Emerging Infectious Diseases, 2012 Two large outbreaks of Ebola hemorrhagic fever occurred in Uganda in 2000 and 2007. In May 2011, we identified a single case of Sudan Ebola virus disease in Luwero District.
Trevor Shoemaker +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Trait-mediated insect colonization of newly established grassland strips in agricultural landscapes
Basic and Applied EcologyRestoring grasslands in agroecosystems through the establishment of grassland and flowering strips has been demonstrated to promote insects. However, the development of the functional composition of insect assemblages in newly established grassland ...
Maria Peer +14 more
doaj +1 more source
Silesians at the Department of Theology of the Krakow University in the 15th century
Folia Historica Cracoviensia, 1996 The establishment of universities in Prague, Vienna and Krakow enabled the Silesians to participate to a greater extent in the university culture of late Middle Ages.
Mieczysław Markowski
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
AgronomyEmpoasca fabae (Harris) is a destructive migratory pest threatening potato cultivation globally. As climate change may facilitate its invasion into China, the world’s largest potato producer, projecting its potential range is critical for early warning ...
Zhendong Gao, Zhuoman Zhang, Hu Li
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Permanent vascular access in patients with end-stage renal disease, Brazil
Revista de Saúde Pública, 2011 OBJECTIVE: To assess factors associated with the establishment of permanent vascular access for patients with end-stage renal disease. METHODS: Cross-sectional study conducted in a nationally representative sample of Brazilian end-stage renal disease ...
Gisele Macedo da Silva +5 more
doaj +1 more source