Results 51 to 60 of about 1,174,554 (297)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
AIP Advances, 2017 In this paper, the partitioned rotor flux switching permanent magnet machine with ferrite permanent magnet is proposed. By the adoption of the partitioned rotor configuration, the stator flux leakage is eliminated and the permanent magnet utilization is ...
Deyang Fan +4 more
doaj +1 more source
Permanent magnet vernier machine: a review
IET Electric Power Applications, 2018 Permanent magnet vernier machines (PMVMs) gained a lot of interest over the past couple of decades. This is mainly due to their high torque density enabled by the magnetic gearing effect. This study will provide a thorough review of recent advances in PMVMs.
Fan Wu, Ayman M. El‐Refaie
openaire +2 more sources
Computation of Optimal Current References for Flux-weakening of Multi-Phase Synchronous Machines [PDF]
, 2012 Multi-phase synchronous machines are more and more used in specific applications where high power density, low bus voltage, wide speed range and fault-tolerant capabilities are required. Due to the high number of degrees of freedom, multi-phase machines
Bassel Aslan +13 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Energies, 2023 Direct-torque-control-driven permanent magnet synchronous machines eliminate the need for a position sensor while providing improved torque dynamics. However, the structure, regulation principle and nature of compensation of hysteresis-based controllers ...
Ibrahim M. Allafi, Shanelle N. Foster
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Design studies of inner and outer embedded Permanent Magnet for hybrid electric vehicles
MATEC Web of Conferences, 2018 Hybrid vehicles require high torque for propel, hence permanent Magnet machines are highly suiting for the improvement in the torque density. The paper focus on designing built-in interior permanent magnet (IPM) synchronous machine for hybrid electric ...
CV Aravind +3 more
doaj +1 more source