Results 61 to 70 of about 128,916 (345)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Materials & Design, 2021 Rare earth permanent magnets are essential in a plethora of electrical machine and renewable energy. Nd-Fe-B magnets account for half of the market share of permanent magnets due to their excellent room temperature magnetic properties.
Zhongwu Liu, Jiayi He, Raju V. Ramanujan
doaj +1 more source
Constructing and Testing a Permanent-Magnet Railgun [PDF]
, 2013 A modified magnetic railgun has been built and investigated. Permanent magnets were used to supply the magnetic field and a car battery was used to provide the current. The projectile has been successfully shot out.
Wu, Yangfan
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Theory of Thermal Remagnetization of Permanent Magnets
, 2001 A self-consistent mean-field theory explaining the thermal remagnetization (TR) of polycrystalline permanent magnets is given. The influence of the environment of a grain is treated by an inclusion approximation, relating the field inside the grain to ...
Adler +20 more
core +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Optimized design of permanent magnet for disk permanent magnet governor
Scientific Reports, 2023 AbstractTo research the magnetic field and mechanical characteristics of the permanent magnet governor, the static magnetic field of the sector permanent magnet is analyzed by the molecular current method in the permanent magnet governor. The magnetic flux distribution is acquired at any spatial position.
Manman Xu +5 more
openaire +3 more sources
Analysis of Axially Magnetized Permanent Magnet Bearing Characteristics [PDF]
, 2012 The use of permanent magnets as bearings has gained attention of researchers nowadays. The characteristics of forces and moments have to be analysed thoroughly for the proper design of permanent magnet bearings.
Anil, TR, Bekinal, SI, Jana, S
core +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source