Results 61 to 70 of about 80,652 (294)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Topology optimized permanent magnet systems [PDF]

open access: yes, 2017
Topology optimization of permanent magnet systems consisting of permanent magnets, high permeability iron and air is presented. An implementation of topology optimization for magnetostatics is discussed and three examples are considered.
Bahl, C. R. H.   +2 more
core   +2 more sources

Optimized design of permanent magnet for disk permanent magnet governor

open access: yesScientific Reports, 2023
AbstractTo research the magnetic field and mechanical characteristics of the permanent magnet governor, the static magnetic field of the sector permanent magnet is analyzed by the molecular current method in the permanent magnet governor. The magnetic flux distribution is acquired at any spatial position.
Manman Xu   +5 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Analysis of Axially Magnetized Permanent Magnet Bearing Characteristics [PDF]

open access: yes, 2012
The use of permanent magnets as bearings has gained attention of researchers nowadays. The characteristics of forces and moments have to be analysed thoroughly for the proper design of permanent magnet bearings.
Anil, TR, Bekinal, SI, Jana, S
core   +1 more source

Permanent Magnet Brushless Drives [PDF]

open access: yesIEEE Industry Applications Magazine, 1998
The purpose of this paper is to present an optimal efficiency control scheme for constant power operation of phase decoupling (PD) PM brushless DC motor drives. The key is to adaptively adjust the advanced conduction angle to minimize the system losses for a given operation point in the constant power region.
Jiang, JZ   +4 more
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Strong magnets with ordered structures

open access: yesMaterials Research Letters, 2022
Permanent-magnet materials are critical components for green energy technologies, but the intrinsic trade-off between saturation magnetization and coercivity limits their achievable energy density. Here, a new concept of ordered structures is proposed to
Hai-Tian Zhang, Xiangyi Zhang
doaj   +1 more source

Reciprocating linear motor [PDF]

open access: yes, 1987
A reciprocating linear motor is formed with a pair of ring-shaped permanent magnets having opposite radial polarizations, held axially apart by a nonmagnetic yoke, which serves as an axially displaceable armature assembly. A pair of annularly wound coils
Goldowsky, Michael P.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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