Results 21 to 30 of about 103 (82)

Numerical simulation on optimization scheme of permeable hole of permeable sheet piling spur dike

IOP Conference Series: Earth and Environmental Science, 2019
Abstract Aimed at the problems about that permeable hole number and permeable hole layout of Permeable Sheet Piling Spur Dike (PSPSD) affecting the flow characteristic at spur dike area, CCHE2D flow simulation mathematical model is adopted, two dimensional flow numerical simulation is carried out for the permeable spur dike area of the ...
Shuaihui Shen, Yujian Li, He Li, Zhaojun Guo, Zhengping Zhou, Liang Mao   +5 more
openaire   +1 more source

Experimental studies on flow profile of permeable spur dikes in upper reaches of Yangtze River

Shuili Shuiyun Gongcheng Xuebao, 2019
The spur dike is one of the most frequently-used hydraulic structures in the waterway regulation works of the upper reaches of the Yangtze River. And in the engineering practice, the riprap permeable spur dikes are often used in the waterway regulation ...
XU Baiqiang, YU Tao, WANG Pingyi, YANG Xiaowen, ZHANG Xiufang   +4 more
doaj   +1 more source

Numerical and experimental investigation for the effect of permeability of spur dikes on local scour [PDF]

Journal of Hydroinformatics, 2019
Abstract The effect of using permeable spur dikes on the produced maximum scour depth compared to that of solid spur dikes is numerically investigated. The numerical model used for such purpose is the Nays-2DH model of the International River Interface Cooperative (iRIC) software package for bed and bank erosion.
openaire   +1 more source

EFFECTS OF PERMEABILITY ON RIVER-BED FORMATION USING SUBMERGED SPUR-DIKE GROUPS

PROCEEDINGS OF HYDRAULIC ENGINEERING, 2008
Continuous submerged groynes can be used to create diverse riverbed configuration. However, scour holes were too large to make groynes unstable in case of impermeable and rigid structures. In order to reduce the scour depth, we used permeable and flexible groynes, that is, gabions.
MATSUMOTO, Daizo, TOMINAGA, Akihiro, ISHIKAWA, Mitsuo   +2 more
openaire   +2 more sources

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

EFFECTS OF PERMEABLE SPUR DIKES ON FLOW AND RIVER BED EVOLUTION IN CURVED OPEN CHANNELS

PROCEEDINGS OF HYDRAULIC ENGINEERING, 2004
The effects of several kinds of permeable spur dike on 3-D flow structures and river bed evolution were investigated in curved open channels experimentally and numerically. In this study, three-dimensional mean flow structures were measured in a curved open channel with spur dikes arranged along the outer bank.
TOMINAGA, Akihiro, NAKAI, Takeshi, NAITO, Ken, NAKAMURA, Naoko   +3 more
openaire   +2 more sources

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source