Results 61 to 70 of about 14,998 (281)

Scope and limitations of the irreversible thermodynamics and the solution diffusion models for the separation of binary and multi-component systems in reverse osmosis process [PDF]

open access: yes, 2017
YesReverse osmosis process is used in many industrial applications ranging from solute-solvent to solvent-solvent and gaseous separation. A number of theoretical models have been developed to describe the separation and fluxes of solvent and solute in ...
Agrawal   +78 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

The origin ofhigh hydraulic resistance for filter cakes ofdef ormable particles: cell-bed deformation or surface-layer effect? [PDF]

open access: yes, 2004
This study reports a numerical approach for modeling the hydraulic resistance ofa filter cake ofdef ormable cells. First, a mechanical and osmotic model that describes the volume fraction ofsolids in a bed ofyeast cells as a function ofthe compressive ...
Aimar, Pierre   +3 more
core   +4 more sources

Modeling of forward osmosis process using artificial neural networks (ANN) to predict the permeate flux

open access: yesDesalination, 2020
Abstract Artificial neural networks (ANN) are black box models that are becoming more popular than transport-based models due to their high accuracy and less computational time in predictions. The literature shows a lack of ANN models to evaluate the forward osmosis (FO) process performance.
Jawad, Jasir   +2 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Ultrafiltration modeling of non-ionic microgels

open access: yes, 2015
Membrane ultrafiltration (UF) is a pressure driven process allowing for the separation and enrichment of protein solutions and dispersions of nanosized microgel particles.
Nägele, Gerhard   +2 more
core   +1 more source

Flux decline in ultrafiltration processes [PDF]

open access: yes, 1990
When a membrane filtration process such as ultrafiltration is used a flux- and yield-decline can be observed. The causes are i) concentration polarization (i.e.
Berg, G.B. van den, Smolders, C.A.
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Implications of inhomogeneous distribution of concentration polarization for interpretation of pressure-driven [PDF]

open access: yes, 2016
A number of CFD studies have demonstrated that there is a considerable inhomogeneity of extent of Concentration Polarization (CP) over the membrane surface especially in spacer-filled feed channels. However, the consequences of this inhomogeneity for the
Fernández de Labastida Ventura, Marcos   +2 more
core   +2 more sources

Permeate Flux Measurement and Prediction of Submerged Membrane Bioreactor Filtration Process Using Intelligent Techniques

open access: yesJurnal Teknologi, 2015
Recently, membrane technology has become more attractive particularly in solid-liquid separation process. Membrane bioreactor (MBR) has found to be a reliable technology to replace the conventional activated sludge (CAS) process for water and wastewater treatment by adopting membrane filtration technology and bioreactor.
Yusuf, Zakariah   +3 more
openaire   +2 more sources

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