Results 101 to 110 of about 17,793,711 (295)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

THE MADRID PROTOCOL: MEWUJUDKAN PERLINDUNGAN HUKUM YANG EFEKTIF BAGI MEREK TERKENAL DI ASEAN

open access: yesJurnal Media Hukum, 2018
Intellectual Property Rights protection system is territorial. Registration and law enforcement must be done separately in each relevant jurisdiction. In the brand regime, this system is often a challenge for brand law enforcement.
rohaini rohaini
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

APK Auditor: Permission-based Android malware detection system

open access: yes, 2015
Android operating system has the highest market share in 2014; making it the most widely used mobile operating system in the world. This fact makes Android users the biggest target group for malware developers.
Aydin, Cetin   +2 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Legislative update [PDF]

open access: yes, 2017
Newsletter of the Teacher Retirement System of Texas providing updated information about programs, benefits, and related ...
Teacher Retirement System of Texas
core  

Malware detection technology analysis and applied research of android platform

open access: yesTongxin xuebao, 2014
For the Android platform security problem, a mobile client and server collaborative malware detection pro-posal was proposed, where mobile client application was mainly based on permission detection technology and imple-mented lightweight testing.
Wei-ping WEN   +3 more
doaj   +2 more sources

Scaling Permissioned Blockchain Systems

open access: yes, 2022
With the advent of Bitcoin, the first real-world and practical blockchain system, researchers and practitioners have turned their eyes and started developing new cryptocurrencies and blockchains. There are two types of blockchains: Permissioned and Permissionless.
openaire   +1 more source

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