Results 91 to 100 of about 339,574 (318)
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Permutation groups containing a regular abelian subgroup: the tangled\n history of two mistakes of Burnside [PDF]
Mark Wildon
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
QUASI-PERMUTATION REPRESENTATIONS OF METACYCLIC 2-GROUPS [PDF]
By a quasi-permutation matrix we mean a square matrix over the complex field C with non-negative integral trace. Thus, every permutation matrix over C is a quasipermutation matrix.
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Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Non-Existence of Perfect Permutation Codes Under Crown Poset Metric
Permutation codes have been extensively investigated using various metrics such as Hamming metric, Ulam metric, Kendall $\tau $ metric, $l_{\infty }$ metric, Cayley metric etc., due to their potential applications in diverse fields such as rank ...
Rohini Baliram More, Venkatrajam Marka
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
On Rational -Valued Characters of Certain Types of Permutation Group
Tow results are proved. The first gives necessary and ullicient conditions for a permutation group to have the prope1ty that each of its rational - valued character can be written as (integral) linear combination of characters induced from ...
M.S Kirdar
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