Results 121 to 130 of about 116,475 (312)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Visualization of finite groups: The case of the Rubik's cube and supporting properties in GeoGebra
Journal of Research and Advances in Mathematics EducationIn this text, we present a discussion about the Rubik's Cube and its relationship with Group Theory, particularly permutation groups, as well as possibilities for exploring it using the GeoGebra software interface.
Renata Teófilo de Sousa +2 more
doaj +1 more source
2-closures of primitive permutation groups of holomorph type
Open Mathematics, 2019 The 2-closure G(2) of a permutation group G on a finite set Ω is the largest subgroup of Sym(Ω) which has the same orbits as G in the induced action on Ω × Ω.
Yu Xue, Pan Jiangmin
doaj +1 more source
Commutators of cycles in permutation groups
Ars Mathematica Contemporanea, 2015 We prove that for n ≥ 5 , every element of the alternating group A n is a commutator of two cycles of A n . Moreover we prove that for n ≥ 2 , a (2 n + 1) -cycle of the permutation group S 2 n + 1 is a commutator of a p -cycle and a q -cycle of S 2 n + 1 if and only if the following three ...
openaire +4 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Permutation-Based Distances for Groups and Group-Valued Time Series
EntropyPermutations on a set, endowed with function composition, build a group called a symmetric group. In addition to their algebraic structure, symmetric groups have two metrics that are of particular interest to us here: the Cayley distance and the Kendall ...
José M. Amigó, Roberto Dale
doaj +1 more source
A Novel Algorithm of Constructing Highly Nonlinear S-p-boxes
Cryptography, 2019 The role of substitution boxes is very important in block ciphers. Substitution boxes are utilized to create confusion in the cryptosystem. However, to create both confusion and diffusion in any cryptosystem p-boxes and chaos base substitution boxes are ...
Yasir Naseer +3 more
doaj +1 more source
On Permutation Groups of Finite Type
European Journal of Combinatorics, 2001 A permutation group \(G\) on a set \(\Omega\) has type \(\{k\}\) (\(k\) a natural number) if every non-identity element has exactly \(k\) fixed points. It is an irredundant group of type \(\{k\}\) if in addition there are no orbits of size one, and no regular orbits.
openaire +3 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source