Results 51 to 60 of about 14,426,649 (305)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

QUASI-PERMUTATION REPRESENTATIONS OF SUZtTKI GROUP [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1999
By a quasi-permutation matrix we mean a square matrix over the complex field C with non-negative integral trace. Thus every permutation matrix over C is a quasipermutation matrix.
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Integrable branes in generalized λ-deformations

open access: yesJournal of High Energy Physics, 2022
We search for integrable boundary conditions and their geometric interpretation as D-branes, in models constructed as generalized λ-deformations of products of group- and coset-spaces.
Georgios P. D. Pappas
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Groups with Two Extreme Character Degrees and their Minimal Faithful Representations [PDF]

open access: yesMathematics Interdisciplinary Research, 2018
for a finite group G, we denote by p(G) the minimal degree of faithful permutation representations of G, and denote by c(G), the minimal degree of faithful representation of G by quasi-permutation matrices over the complex field C.
Mahtab Delfani, Houshang Behravesh
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Variational quantum algorithms for permutation-based combinatorial problems: Optimal ansatz generation with applications to quadratic assignment problems and beyond [PDF]

open access: yesQuantum
We present a quantum variational algorithm based on a novel circuit that generates all permutations that can be spanned by one- and two-qubits permutation gates.
Dylan Laplace Mermoud   +2 more
doaj   +1 more source

The leading coefficient of certain Kazhdan–Lusztig polynomials of the permutation group Sn [PDF]

open access: yes, 2004
In this paper we show that the leading coefficient μ ( y , w ) of certain Kazhdan–Lusztig polynomials P y , w of the permutation group S n of 1 , 2 , … , n are not greater than 1.
N. Xi
semanticscholar   +1 more source

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