Results 81 to 90 of about 339,574 (318)
The Valence-Bond (VB) Model and Its Intimate Relationship to the Symmetric or Permutation Group. [PDF]
Molecules, 2021 Nascimento MAC.
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
A Novel Algorithm of Constructing Highly Nonlinear S-p-boxes
Cryptography, 2019 The role of substitution boxes is very important in block ciphers. Substitution boxes are utilized to create confusion in the cryptosystem. However, to create both confusion and diffusion in any cryptosystem p-boxes and chaos base substitution boxes are ...
Yasir Naseer +3 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
An Image Encryption Algorithm Based on Time-Delay and Random Insertion
Entropy, 2018 An image encryption algorithm is presented in this paper based on a chaotic map. Different from traditional methods based on the permutation-diffusion structure, the keystream here depends on both secret keys and the pre-processed image.
Xiaoling Huang, Guodong Ye
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Extensions of a theorem of Jordan on primitive permutation groups [PDF]
, 1983 Martin W. Liebeck
openalex +1 more source
Quantum-Inspired Optimization over Permutation Groups [PDF]
, 2022 Rathi Munukur +3 more
openalex +1 more source