Results 101 to 110 of about 97,370 (265)

A New F-Test Applicable to Large-Scale Data

open access: yesJournal of Statistical Theory and Applications (JSTA), 2019
In large-scale multiple testing, the permutation test based on making a null statistic has been widely employed in the literature. Because it enables us to use the null permuted samples and estimate the p-value more accurately.
Mohsen Salehi   +2 more
doaj   +1 more source

On Permutation Groups of Finite Type

open access: yesEuropean Journal of Combinatorics, 2001
A permutation group \(G\) on a set \(\Omega\) has type \(\{k\}\) (\(k\) a natural number) if every non-identity element has exactly \(k\) fixed points. It is an irredundant group of type \(\{k\}\) if in addition there are no orbits of size one, and no regular orbits.
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

On a question of permutation groups acting on the power set

open access: yesOpen Mathematics
In this work, we settle a conjecture about the number of set-orbits of permutation group acting on the power set.
Li Jinbao, Yang Yong, You Mengxi
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Fault Diagnosis for Rolling Element Bearings Based on Feature Space Reconstruction and Multiscale Permutation Entropy

open access: yesEntropy, 2019
Aimed at distinguishing different fault categories of severity of rolling bearings, a novel method based on feature space reconstruction and multiscale permutation entropy is proposed in the study.
Weibo Zhang, Jianzhong Zhou
doaj   +1 more source

Combinatorial categories and permutation groups

open access: yesArs Mathematica Contemporanea, 2015
The regular objects in various categories, such as maps, hypermaps or covering spaces, can be identified with the normal subgroups N of a given group Γ, with quotient group isomorphic to Γ/N. It is shown how to enumerate such objects with a given finite automorphism group G, how to represent them all as quotients of a single regular object U(G), and ...
openaire   +4 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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