Results 41 to 50 of about 278,863 (274)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
This paper presents an effective stochastic algorithm that embeds a large neighborhood decomposition technique into a variable neighborhood search for solving the permutation flow-shop scheduling problem. The algorithm first constructs a permutation as a
Mehrdad Amirghasemi
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Classification of four-point local gluon S-matrices
In this paper, we classify four-point local gluon S-matrices in arbitrary dimensions. This is along the same lines as [1] where four-point local photon S-matrices and graviton S-matrices were classified.
Subham Dutta Chowdhury, Abhijit Gadde
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Visualization of finite groups: The case of the Rubik's cube and supporting properties in GeoGebra
In this text, we present a discussion about the Rubik's Cube and its relationship with Group Theory, particularly permutation groups, as well as possibilities for exploring it using the GeoGebra software interface.
Renata Teófilo de Sousa +2 more
doaj +1 more source
Computing Minimal Generating Sets of Invariant Rings of Permutation Groups with SAGBI-Gröbner Basis [PDF]
We present a characteristic-free algorithm for computing minimal generating sets of invariant rings of permutation groups. We circumvent the main weaknesses of the usual approaches (using classical Gröbner basis inside the full polynomial ring, or pure ...
Nicolas Thiéry
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

