Results 71 to 80 of about 177,217 (207)

Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease

Immunology &Cell Biology, Volume 104, Issue 6, Page 613-630, July 2026.
The T cell momentum assay quantifies division, survival and activation decay to reveal intrinsic CD4+ programming defects marked by prolonged activation and impaired feedback control in coeliac disease. This scalable platform provides a functional screen for early T cell dysregulation across autoimmune and immune‐mediated diseases.
Anthony J Farchione, HoChan Cheon, David Vremec, Julika Neumann, Gwenny M Verstappen, Melinda Y Hardy, Mai B Margetts, Lauren J Howson, Lee M Henneken, Maureen Forde, Jason A Tye‐Din, Susanne Heinzel, Philip D Hodgkin, Vanessa L Bryant   +13 more
wiley   +1 more source

Clinical case of pernicious anemia

Vitamin B12 - deficiency anemia (pernicious anemia, Addison-Biermer disease) – megaloblastic anemia, arising due to the deficiency of cyanocobalamin in the body, characterized by impaired erythropoiesis, damage to the hematopoietic tissue, digestive and ...
V. Arhipenko
core   +1 more source

Association of Type 2 Diabetes Mellitus With Dietary Vitamin B12 Intake in Individuals With Different Fat Mass and Obesity‐Associated (FTO) Genotypes

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Higher dietary vitamin B12 intake was inversely associated with the odds of type 2 diabetes mellitus among individuals carrying the TT genotype of the FTO rs9939609 polymorphism. These findings highlight the potential role of precision nutrition strategies in diabetes prevention.
Elham Nikoei Foshtomi, Atefeh Tahavorgar, Ali Shamsi‐Goushki, Mahsa Vahdat, Pegah Samani, Maryam Shojaei, Mohammadtaghi Ghorbani Hesari, Ali Moradi, Morteza Abdollahi, Anahita Houshyar Rad, Saeid Doaei, Marjan Ajami, Maryam Gholamalizadeh   +12 more
wiley   +1 more source

A long-standing undiagnosed case of vitamin B12 deficiency: a case report

Journal of Medical Case Reports
Background Pernicious anemia, an autoimmune disease, presents with gradual, nonspecific symptoms, often leading to delayed diagnosis owing to its overlap with other conditions and variability in laboratory findings, such as neurological symptoms without ...
Amirhossein Mesgarankarimi, Maryam Rezapour, Nasim Tabrizi   +2 more
doaj   +1 more source

Efficacy of Ritlecitinib for Vitiligo Treatment Stratified by Baseline Demographic and Clinical Characteristics: Post Hoc Analysis of a Phase 2b Study

JEADV Clinical Practice, Volume 5, Issue 2, Page 571-576, June 2026.
This post hoc analysis examined the efficacy of ritlecitinib in subgroups of patients with vitiligo, defined by demographic and clinical characteristics. Patients completed the dose‐ranging and extension periods of the phase 2b study (NCT03715829) of ritlecitinib.
A. G. Pandya, I. Hamzavi, P. Ghosh, K. Ezzedine, J. E. Harris, R. Adiri, S. Chen, E. Peeva, Y. Yamaguchi   +8 more
wiley   +1 more source

An Uncommon Association: HLA-B27 Positivity in Conjunction With Pernicious Anemia - A Case Report and Literature Review. [PDF]

J Community Hosp Intern Med Perspect
Pernicious anemia, stemming from Vitamin B12 deficiency and autoimmune processes affecting intrinsic factor production, presents challenges in early diagnosis due to vague initial symptoms.
Auda AH, Atoot R, Jurri M, Mahmoud A, Siddiqui A, Bangolo A, Malik T, Baker I, Sotiriadis J.   +8 more
europepmc   +2 more sources

Significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in atrophic glossitis patients

Journal of the Formosan Medical Association, 2018
Background/Purpose: Atrophic glossitis (AG) patients are prone to have anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity.
Chun-Pin Chiang, Julia Yu-Fong Chang, Yi-Ping Wang, Yang-Che Wu, Yu-Hsueh Wu, Andy Sun   +5 more
doaj   +1 more source

Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with vitamin B12 deficiency

Journal of the Formosan Medical Association, 2020
Background/Purpose: Our previous study found that 56 of 1064 atrophic glossitis (AG) patients have vitamin B12 deficiency. This study assessed whether the AG patients with vitamin B12 deficiency (B12D/AG patients) had significantly higher frequencies of ...
Yang-Che Wu, Yu-Hsueh Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Ying-Shiung Kuo, Andy Sun   +5 more
doaj   +1 more source

Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4653-4670, June 2026.
ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram, Marine Corbin, Andrea ’t Mannetje, Jeroen Douwes, Amanda Kvalsvig, Amanda Eng   +5 more
wiley   +1 more source

Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in atrophic glossitis patients with iron deficiency

Journal of the Formosan Medical Association, 2020
Background/Purpose: Our previous study found that 180 of 1064 atrophic glossitis (AG) patients have iron deficiency. This study assessed whether all AG patients with iron deficiency (so-called ID/AG patients) had iron deficiency anemia (IDA) and ...
Chun-Pin Chiang, Yang-Che Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Yu-Hsueh Wu, Andy Sun   +5 more
doaj   +1 more source