Results 201 to 210 of about 453,099 (256)
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Radiation Research Supplement, 1963
The role of peroxides, produced by radiation or oxidative processes in metabolism, in the production of mutations is reviewed. Results are reported from studies on living cells immersed in peroxides modified in various ways. Results are used to postulate the action of internally formed peroxides on the hereditary substance. It is concluded that it will
O, WYSS, C, WIESEN, G E, SCHAIBERGER
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The role of peroxides, produced by radiation or oxidative processes in metabolism, in the production of mutations is reviewed. Results are reported from studies on living cells immersed in peroxides modified in various ways. Results are used to postulate the action of internally formed peroxides on the hereditary substance. It is concluded that it will
O, WYSS, C, WIESEN, G E, SCHAIBERGER
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Lipid peroxidation and lipid peroxide detected by chemiluminescence
Free Radical Biology and Medicine, 1987This article emphasizes the advantages of using a luminescence spectrometer based on photon counting techniques for the detection of lipid peroxidation. An overview is presented of how chemiluminescence can be stimulated in the luminol-cytochrome c heme peptide system as an assay for lipid hydroperoxides.
T, Iwaoka, F, Tabata, T, Takahashi
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Hydrogen peroxide and hematin in microsomal lipid peroxidation
Journal of Inorganic Biochemistry, 1981Lipids of rat liver microsomes underwent peroxidation with production of malondialdehyde in the presence of H2O2 and hematin. Rates of peroxidation of 27-33 nmol of MDA formed/mg of microsomal protein/30 min were measured with 5 mM H2O2 and 10 microM hematin at 22 degrees C. Histidine (0.01 M) caused a 55% inhibition.
URSINI, FULVIO +4 more
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The Lancet, 1988
Free-radical-mediated lipid peroxidation has become closely associated with destructive biochemical processes and, more recently, with disease. Its potential survival value may be overlooked.
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Free-radical-mediated lipid peroxidation has become closely associated with destructive biochemical processes and, more recently, with disease. Its potential survival value may be overlooked.
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Organic Peroxides, Hydrogen Peroxide, Epoxides, and Neoplasia
Radiation Research Supplement, 1963Preliminary data are reported that support the suspicion that organic peroxides may possess carcinogenic properties. This suspicion in large measure relates to the acknowledged mutagenicity of certain peroxides. As a possible mechanism of action it is suggested that peroxides may act by catalyzing the depolymerization of deoxyribonucleic (DNA) and ...
P, KOTIN, H L, FALK
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Hematin- and peroxide-catalyzed peroxidation of phospholipid liposomes
Archives of Biochemistry and Biophysics, 1991The effect of hydroperoxides on hematin-catalyzed initiation and propagation of lipid peroxidation was examined utilizing soybean phosphatidylcholine liposomes as model membranes. Polarographic and spectrophotometric methods revealed a bimodal pseudocatalytic activity for hematin.
E H, Kim, A, Sevanian
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Synthetic peroxides as antimalarials
Medicinal Research Reviews, 2004AbstractThe discovery of artemisinin in 1971 initiated a new era in antimalarial chemotherapy. Although the clinically useful semisynthetic artemisinin derivatives are rapid acting and potent antimalarial drugs, they have short half‐lives and must be administered over a period of 5–7 days, leading to noncompliance and recrudescence.
Yuanqing, Tang +2 more
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Coulometric microdetermination of peroxides—II☆Organic peroxides
Talanta, 1973An iodometric method for the rapid microdetermination of organic peroxides, utilizing electrochemical reduction in the iodine-iodide system, has been developed. After complete reaction between peroxide and iodide in an acidic semi-aqueous medium the iodine produced is reduced at a rotating platinum electrode, at constant potential.
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Coulometric microdetermination of peroxides—I. Hydrogen peroxide
Talanta, 1973An electroanalytical method, based on controlled-potential coulometry in the iodine-iodide system, has been developed for determination of small amounts of hydrogen peroxide. The sample is added to an electrolyte containing an acid solution of iodide and the iodine, which is produced rapidly, is reduced at a rotating platinum electrode.
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A nonenzymatic method for determination of hydrogen peroxide and organic peroxides
Analytical Biochemistry, 1987Reduction of hydrogen peroxide and organic peroxides (t-butyl hydroperoxide and linoleic acid hydroperoxide) was achieved with homovanillic acid as hydrogen donor in the presence of the triethylenetetramine-Fe3+ complex. By the catalytic action of this complex, homovanillic acid is oxidized to its fluorescent dimer.
R, Ebermann, A, Couperus
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