Results 211 to 220 of about 55,491 (291)

Rethinking colitis: MrgprD puts macrophages in the driver's seat†

The Journal of Pathology, EarlyView.
Abstract There is increasing evidence to suggest that dysregulated macrophages play an important role in the promotion and maintenance of inflammatory bowel disease (IBD), yet the underlying mechanisms remain unclear. A recent study published by Lv, Xia, Qiao et al in The Journal of Pathology investigated the role of Mas‐related G protein‐coupled ...
Kolja Pocha, Konstantin Bräutigam
wiley   +1 more source

Berberine-Drug Interactions: Mechanisms, Clinical Relevance and Risk Stratification-A Narrative Review. [PDF]

Pharmaceuticals (Basel)
Dumitru CN, Marcu T, Dumitru AO, Tudor SS, Ferțu ID, Elisei AM, Goroftei L.   +6 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Psychometric dataset of the Indonesian adaptation of the adolescent peer relations instrument (APRI) bullying perpetration subscale among Indonesian senior high school students. [PDF]

Data Brief
Arya L, Abdullah AF, Sulaeman B, Nurahaju R, Handayani WD, Suwasono B.   +5 more
europepmc   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Understanding cyber grooming in children and adolescents: a scoping review of risk factors and prevention strategies. [PDF]

Front Psychiatry
Kaya K, Erdem Z.
europepmc   +1 more source

Can Financial Development and Renewable Energy Drive Production‐Based and Consumption‐Based Carbon Emissions Reductions in E7 Economies?

Sustainable Development, EarlyView.
ABSTRACT The growing intensity of climate change calls for a more comprehensive understanding of how energy use and financial systems influence global carbon emissions. So far, existing research and policy efforts have mainly focused on production‐based emissions (PCO2).
Siyu Sun, Amber Pervaiz, Antonio Cimino
wiley   +1 more source

A collaborative approach to applying Natural Language Processing (NLP) to Domestic Homicide Reviews (DHRs): A study protocol. [PDF]

PLoS One
Cook D, Cook EA, Roy S, Thiara R, Selvarajah R.   +4 more
europepmc   +1 more source

Towards Responsible Mining in Africa: Problematising the Environmental and Public Health Concerns of Artisanal and Small‐Scale Gold Mining in Ghana

Sustainable Development, EarlyView.
ABSTRACT There have been emerging media reports on the impact of cyanide and mercury use in artisanal and small‐scale gold mining (ASGM) operations on community health, especially among pregnant and non‐pregnant women, ASGM miners, and children in rural Africa.
Francis Arthur‐Holmes, Emmanuel Selasi Tomude, Steve Ahenkora Amoako   +2 more
wiley   +1 more source

Hospital-Based Shootings in the US, 2000-2024: A Systematic Review.

JAMA Netw Open
Wanberg EJ, Hooper CC, Clements CM, Gerberi DJ, Mullan AF, McGuire SS.   +5 more
europepmc   +1 more source