Results 131 to 140 of about 7,144 (220)
Convection‐Permitting Regional Climate Simulations Reveal Stronger Drying and Snow Loss in Semi‐Arid Mountainous Basins of Morocco
Hydrological Processes, Volume 40, Issue 6, June 2026.Convection‐permitting simulations (WRF3, 3 km) better represent mountain precipitation and snow processes than coarser regional simulations (WRF20, 20 km). Hydrological simulations forced by WRF3 improve streamflow seasonality and snow‐related hydrological signatures compared to WRF20.Ouiaam Lahnik, Yves Tramblay, Redouane Lguensat, Sophie Bastin, Yoann Robin, Jafet C. M. Andersson, Lahoucine Hanich +6 morewiley +1 more sourceAnnexin A6 Modulates the Secretion of Pro-Inflammatory Cytokines and Exosomes via Interaction with SNAP23 in Triple-Negative Breast Cancer Cells. [PDF]
CellsSakwe NI, Korolkova OY, Vuong NB, Edwards AD, Black PJ, Ball DD, McIntosh AR, Thomas PL, Whalen Melvin DS, Beasley HK, Hinton AO, Ochieng J, Sakwe AM. +12 moreeuropepmc +1 more sourceSufficiency of current practice: How well does the Strengths and Difficulties Questionnaire detect clinically elevated posttraumatic stress, anxiety, and depression symptoms in children in care?
JCPP Advances, Volume 6, Issue 2, June 2026.Abstract Background
It is well‐established that children living in care are at far greater risk of mental health difficulties than their peers. This includes common and trauma‐specific mental health conditions, including depression, anxiety and posttraumatic stress disorder (PTSD).Eva A. Sprecher, Katherine Shelton, Lisa Holmes, Bethan Carter, Charlotte Robinson, Maryam Javed, Ruby Khan, John MacLeod, Jeongeun Park, Julie Selwyn, Iram Siraj, Ching So, Rachel M. Hiller +12 morewiley +1 more sourceIdentification and Functional Characterization of Isoflavone synthase Gene Family in Pea (Pisum sativum): The Entry Point to Pisatin Biosynthesis
Legume Science, Volume 8, Issue 2, June 2026.ABSTRACT
Isoflavone synthase (IFS), a cytochrome P450 monooxygenase of the CYP93C subfamily, catalyzes the conversion of flavanones into isoflavones, the first committed step in the biosynthesis of isoflavonoid phytoalexins. In pea (Pisum sativum L.), the phytoalexin pisatin plays a pivotal role in defense against pathogens.Muhammad Sufyan Tahir, Kuflom Kuflu, Nishat Shayala Islam, Tim McDowell, Sangeeta Dhaubhadel +4 morewiley +1 more sourceGene-edited pig cardiac xenotransplantation as a bridge to allotransplantation in infants: Progress in a pig-to-baboon model. [PDF]
Am J TransplantCleveland JD, Mitchell CB, Swicord W, Neal SJ, Vo C, Bakshi K, Juliani J, Fenske J, De La Garza M, Hodo CL, Chitta S, Getchell K, Moreno I, Yeung V, Low S, Perrin S, Katz E, Weisert M, Cooper DKC, Simmons J, Cleveland DC. +20 moreeuropepmc +1 more sourceSex Determination in Sponges
Molecular Reproduction and Development, Volume 93, Issue 6, June 2026.ABSTRACT
Sex determination in Porifera remains one of the least understood aspects of early metazoan biology despite the group's key phylogenetic position. Sponges display exceptional diversity in sexual systems—ranging from stable gonochorism to sequential hermaphroditism and sex reversal—yet lack morphological dimorphism and any discrete gonadal ...Jose M. Lorente‐Sorolla, Ana Riesgowiley +1 more sourceCharacteristics, treatment and survival of older patients with metastatic triple negative breast cancer from the ESME mBC real-world national cohort: a comparison with younger women. [PDF]
BreastMairé M, Bouteiller F, Chakiba C, Jacot W, Geiss R, Ung M, Goncalves A, Frenel JS, Bailleux C, Perrin C, Massard V, Mailliez A, Jouannaud C, Cherifi F, Petit T, Terret C, Viansone A, Bosquet L, Galvin A. +18 moreeuropepmc +1 more sourcePhysiologically Based Pharmacokinetic Modeling of Elexacaftor/Tezacaftor/Ivacaftor in Infants With Cystic Fibrosis
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.ABSTRACT
Ivacaftor is the only cystic fibrosis transmembrane conductance regulator modulator approved for infants ≥ 1 month. The elexacaftor/tezacaftor/ivacaftor combination, approved for children aged ≥ 2 years, has been shown to significantly slow CF progression.Ngoc Hoa Truong, Sihem Benaboud, Naïm Bouazza, Eric Deneuville, Anne Mornand, Philippe Reix, Mélanie Ribault, Pierre‐Régis Burgel, Léo Froelicher‐Bournaud, Steeve Rouillon, Mohammed Rohi Sanoufi, Gabrielle Lui, Saïk Urien, Jean‐Marc Tréluyer, Isabelle Sermet‐Gaudelus, Frantz Foissac, Modul‐CF study group, Melissa Baravalle, Mahassen Barboura, Lilia Benhalla, Khadidja Bennour, Katia Bessaci, Antoine Bessou, Thiphaine Bihouée, Anne‐Sophie Bonnel, Nesrine Bouleghem, Stéphanie Bui, Frédérique Chedevergne, Harriet Corvol, Laure Cosson, Laure Couderc, Marie‐Laure Dalphin, Paola De Carli, Eric Deneuville, Pierre Foucaud, Asma Gabsi, Elsa Gachelin, Fatiha Hassani, Véronique Houdouin, Frédéric Huet, Marie Jamin, Kadiatou Kaba, Guillaume Labbé, Jane Languepin, Muriel Laurans, Cathy Léréna, Alexia Letierce, Clotilde Livrozet, Christophe Marguet, Laurent Mély, Rania Messaoudi, Marie Mittaine, Camille Ohlmann, Caroline Périsson, Thomas Perrin, Carole Piccini‐Bailly, Cinthia Rames, Philippe Reix, Natascha Rémus, Anna Ronayette, Djouher Sahki, Manuela Scalbert, Isabelle Sermet, Floriane Socchi, Nathalie Stremler, Aurélie Tatopoulos, Guillaume Thouvenin, Tom Toin, Françoise Troussier, Laurence Weiss, Marie‐Christine Werck‐Galois, Nathalie Wizla +71 morewiley +1 more source