Results 221 to 230 of about 45,168 (300)

Critical Assessment of a Structure-Based Pipeline for Targeting the Long Noncoding RNA MALAT1. [PDF]

J Chem Inf Model
Aguti R, Bernetti M, Elisi GM, Cavalli A, Masetti M.   +4 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Demonstrating the principal mechanism of action of medical devices intended for vaginal use on reconstructed human vaginal epithelium: the case of two hyaluronic acid-containing devices. [PDF]

Front Drug Saf Regul
Meloni M, De Servi B, Carriero F, Simon O'Brien E, Houamel D, Deruelle P, Castagné V.   +6 more
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Characterising the performance of a drone-mounted real-time methane imaging system. [PDF]

Sci Rep
MacGruer AG, Johnson SD, Mekhail SP, Nutt KJ, Padgett MJ, Gibson GM.   +5 more
europepmc   +1 more source

Reducing bullying amongst the worst affected [PDF]

, 2010

core  

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Collecting Real-World Data via an In-Home Smart Medication Dispenser: Longitudinal Observational Study of Survey Panel Persistency, Response Rates, and Psychometric Properties.

JMIR Hum Factors
Ogorek B, Rhoads T, Smith E.
europepmc   +1 more source

Evaluating Patient Adherence and Persistence to Tyrosine-Kinase Inhibitors for Metastatic Renal Cell Carcinoma: A Retrospective Analysis of Real-World Data. [PDF]

Clin Med Insights Oncol
Arter ZL, Benjamin DJ, Cao Y, Farias J, Thirumaran RK, Forsyth M, Mar N, Rezazadeh Kalebasty A.   +7 more
europepmc   +1 more source

Persistent Pneumothorax [PDF]

Proceedings of the Royal Society of Medicine, 1929
openaire   +2 more sources