Results 241 to 250 of about 151,252 (289)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

RFID-ExSim: A multi-scenario experimental dataset for collision timing, tag cloning, replay injection, and flooding stress in passive RFID systems. [PDF]

Data Brief
Hmimou Y, Boutlane M, Tabaa M, Khiat A, Hidila Z.   +4 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Evaluation of the Antimicrobial Efficacy of Cerium Oxide Nanoparticles and Chlorhexidine Gluconate Against Enterococcus faecalis in Root Canal Systems: Protocol for an In Vitro Study.

JMIR Res Protoc
Khanadali BS, Ikhar A.
europepmc   +1 more source

Exploring the role of blinatumomab in pediatric B-lymphoblastic lymphoma (B-LLy). [PDF]

Blood Adv
Devine KJ, Fries C, Wistinghausen B.
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Antibody escape drives emergence of diverse spike haplotypes resembling variants of concern in persistent SARS-CoV-2 infections. [PDF]

Cell Rep Med
Snell LB, Pickering S, Alcolea-Medina A, Winstone H, Seow J, Graham C, O'Connell L, Batra R, Malim MH, Doores KJ, Nebbia G, Edgeworth JD, Neil SJD, Galão RP.   +13 more
europepmc   +1 more source

Selumetinib as an Effective Therapy of Histiocytic Sarcoma Evolving From a B-Cell Acute Lymphoblastic Leukaemia. [PDF]

EJHaem
Largeaud L, Syrykh C, Vial J, Canali A, Luquet I, Vergez F, Dufrechou S, Prade N, Baruchel A, Gerby B, Nolla M, Delabesse E, Pasquet M.   +12 more
europepmc   +1 more source

Bilateral Anterior Shoulder Dislocations: A Narrative Review and Case Report. [PDF]

Cureus
Tierney J, Waugh D, Putti A.
europepmc   +1 more source

Mid-Regional Pro-Adrenomedullin as a Translational Biomarker of Microcirculatory Dysfunction in Sepsis: A Prospective Observational Study. [PDF]

Med Sci (Basel)
Cusack R, Garduno A, Cumpf S, Reyes-Morales P, Leone M, Fernández AB, Rodriguez A, Martin-Loeches I.   +7 more
europepmc   +1 more source