Results 81 to 90 of about 1,889,632 (199)

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora   +8 more
wiley   +1 more source

Expert Consensus on the Diagnosis and Monitoring of Paroxysmal Nocturnal Hemoglobinuria (PNH): An Algorithmic Approach in an Era of New Treatments

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder caused by a defect of glycosylphosphatidyl‐anchored proteins, leading to an uncontrolled complement‐mediated hemolysis. The advent of complement inhibitors in clinical practice radically changed patients' outcomes and survival.
Bruno Fattizzo   +8 more
wiley   +1 more source

Association Between Coping Strategies and Pain-Related Outcomes Among Individuals with Chronic Orofacial Pain

open access: yesJournal of Pain Research, 2022
Jonathan Greenberg,1– 3 Jafar Bakhshaie,1– 3 Brenda C Lovette,3,4 Ana-Maria Vranceanu1– 3 1Integrated Brain Health Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; 2Harvard Medical School, Boston ...
Greenberg J   +3 more
doaj  

When persistent idiopathic facial pain is not idiopathic: Facial pain attributed to lung cancer and comparative review of classification systems

open access: yesCRANIO®
Facial pain attributed to lung cancer (FPLC) is frequently misclassified as persistent idiopathic facial pain (PIFP). This study reviewed published cases, retrospectively applied existing criteria for PIFP to evaluate misclassification, characterized clinical features of FPLC, and proposed a diagnostic framework. A structured search of MEDLINE, Embase,
Shehryar N. Khawaja, Madha Mansoor
openaire   +2 more sources

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Computed tomographic diagnosis and treatment of pneumolabyrinth in a mare with temporohyoid osteoarthropathy

open access: yesEquine Veterinary Education, EarlyView.
Summary Pneumolabyrinth, which is the presence of gas within the labyrinth of the inner ear, can be associated with severe peripheral vestibular signs. This report describes a case of pneumolabyrinth in a horse that presented with vestibular ataxia. An 8‐year‐old Quarter Horse mare that presented with cranial nerve VII deficits underwent a standing ...
C. A. Jamieson   +5 more
wiley   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

open access: yesInternational Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta   +4 more
wiley   +1 more source

Management of persistent idiopathic facial pain (PIFP) – An international Delphi study

open access: yesCephalalgia
Background/Aim Persistent idiopathic facial pain (PIFP) is a rare condition with a lifetime prevalence of approximately 0.03%. It is characterized by persistent daily facial pain without identifiable cause and presents diagnostic and therapeutic challenges due to unknown pathophysiology, symptom overlap with ...
Erik Lindfors   +18 more
openaire   +4 more sources

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

Case report: radiofrequency neuroablation of the sphenopalatine ganglion in persistent idiopathic facial pain associated with fibromyalgia

open access: yesHeadache Medicine
Introduction Persistent idiopathic facial pain (PIFP) is a neuropathic craniofacial pain disorder that may phenotypically overlap with refractory headache syndromes, frequently resulting in delayed diagnosis, polypharmacy, and pain chronification ...
Ana Beatriz Dantas Brandini   +3 more
doaj   +2 more sources

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