Results 191 to 200 of about 2,464,313 (253)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Factors Associated With Persistent Symptoms Following Mild Traumatic Brain Injury.

JAMA Netw Open
Peacock WF, Kuehl D, Diaz-Arrastia R, Vanlandingham J, Than M, Cannon CM, Singer AJ, Mirshahi N, Weppner J, Gerwien R.   +9 more
europepmc   +1 more source

Feasibility of an unsupervised aerobic exercise training program for participants with persistent symptoms after SARS-CoV-2 infection. [PDF]

Sci Rep
Emmel C, Bruder O, Keller N, Schipper L, Schneider C, Ferrauti A, Frank M, Brinkmann M, Eißmann M, Wiewelhove T, Schmidt B.   +10 more
europepmc   +1 more source

Charting Endocrine Progenitors Across Species and Organs

Advanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing, Michael Sterr, Özüm Sehnaz Caliskan, Lama Saber, Nicole Katarina Rogers, Samuel Ogden, Kei Kozawa, Christos Karampelias, Jessica Jaki, Aimée Bastidas‐Ponce, Falk Janos Farkas, Oliver Czarnecki, Osvaldo Rodrigues Pereira, Perla Cota, Valerie Vandenbempt, Diego Balboa, Anika Böttcher, Natalie Krahmer, Mohammad Lotfollahi, Julie B. Sneddon, Heiko Lickert, Mostafa Bakhti   +21 more
wiley   +1 more source

Evaluating the efficacy of a personalised sub-symptomatic exercise treatment programme for rehabilitation of military service members with persistent symptoms following mild traumatic brain injury: a randomised controlled trial. [PDF]

BMJ Open Sport Exerc Med
Darr AJ, Kirlin LK, Lopez J, Caswell M, Ananthanarayanan M, Robb J, Haider MN, Kelly KR, Bailie JM.   +8 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A pilot study of disulfiram for individuals with persistent symptoms despite prior antibiotic treatment for Lyme disease. [PDF]

Front Med (Lausanne)
Kuvaldina M, Preston J, McClellan D, Pavlicova M, Brannagan TH, Fallon BA.   +5 more
europepmc   +1 more source

Critical Approach to Hypothyroid Patients With Persistent Symptoms.

J Clin Endocrinol Metab, 2023
Biondi B, Celi FS, McAninch EA.
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

A double-blind randomized trial of hyperbaric oxygen for persistent symptoms after brain injury. [PDF]

Sci Rep
Weaver LK, Ziemnik R, Deru K, Russo AA.
europepmc   +1 more source