Results 41 to 50 of about 657,319 (150)

Wt1 Is Required for the Regression of Müllerian Ducts in Male Mice by Inducing Wif1 and Osx Expression

Cell Proliferation, EarlyView.
Wt1 expressed in the MD mesenchyme promotes MD regression by inducing Wif1 and Osx transcription. In male mice, mesenchyme‐specific inactivation of Wt1 results in MD retention. ABSTRACT In mammals, Müllerian ducts (MDs) are the precursors of the female reproductive tract which regress in males during embryonic development.
Min Chen, Xin Qi, Shanshan Qin, Jia Kang, Changhuo Cen, Miao Guo, Yang Gao, Mengyue Wang, Jiayi Li, Xiuhong Cui, Yanbo Wang, Lan Zhu, Fei Gao   +12 more
wiley   +1 more source

Prostate Development Requires Sonic Hedgehog Expressed by the Urogenital Sinus Epithelium [PDF]

, 1999
The prostate gland develops from the urogenital sinus by a testosterone-dependent process of ductal morphogenesis.Sonic hedgehog(Shh) is expressed in the urogenital sinus epithelium and the time course of expression coincides with the formation of the ...
Clemens, J.Quentin, Podlasek, Carol A, Barnett, Daniel H, Bak, Philip M, Bushman, Wade   +4 more
core   +1 more source

Chronic inflammation of the bladder as a result of persistent urogenital sinus in girls with a classical form of 21-hydroxylase deficiency

Russian Journal of Pediatric Surgery, 2023
Introduction. The choice of tactics for surgical correction of virilized genitalia in girls with the classic form of congenital adrenal hyperplasia (CAH) remains a topical issue in pediatric surgery. The early one-stage feminization in severe forms of genital virilization, in case of urogenital sinus, is recommended by the international guidelines on ...
A. V. Anikiev, D. N. Brovin, E. A. Volodko, O. Yu. Latyshev   +3 more
openaire   +1 more source

Simultaneous Ureterovaginal and Rectovaginal Fistulas Caused by a Cube Pessary: A Case Report

IJU Case Reports, Volume 9, Issue 6, November 2026.
ABSTRACT Introduction We present a case of simultaneous ureterovaginal and rectovaginal fistulas caused by continuous placement of a cube pessary without daily removal, successfully managed through a multidisciplinary approach. Case Presentation An 84‐year‐old female managed with a cube pessary presented with hematochezia.
Tetsuhiro Yano, Yutaro Sasaki, Riyo Kinouchi, Hideya Kashihara, Haruka Itami, Saki Kobayashi, Tomoya Fukawa, Takeshi Iwasa, Akihiko Soyama, Junya Furukawa   +9 more
wiley   +1 more source

Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness

The Prostate, Volume 86, Issue 15, Page 1508-1517, November 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen, Fulu Dong, Mohammad Reza Askarpour, Laura E. Pascal, Rajiv Dhir, Uma Chandran, Bruce L. Jacobs, Donald B. DeFranco, Naoki Yoshimura, Zhou Wang   +9 more
wiley   +1 more source

Case Report Isolated Fetal Ascites Secondary to Persistent Urogenital Sinus [PDF]

, 2009
Objective. To present a case of isolated ascites secondary due to urogenital abnormalities (urogenital sinus) without any other prenatal ultrasound marker. Method. A 36-year-old woman with prenatal isolated ascites delivered a female baby, weighing 2.285
D Camanni, A Zaccara, I Capolupo, G Mosiello, M De Gennaro, M L Capitanucci, B D Iacobelli   +6 more
core  

Persistent urogenital sinus with recto-vaginal fistula: the new variant in which the anus is normally positioned and literature review

Annals of Pediatric Surgery, 2023
Abstract Background Persistent urogenital sinus is a rare cloacal anomaly in which the urinary and genital tracts cannot be differentiated during embryonic development. However, the presence of concomitant recto-urogenital sinus or recto-vaginal fistula is much rarer.
Hikmet Zeytun, Ahmet Demez, Bulent Hayri Ozokutan   +2 more
openaire   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2181-2198, October 2026.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 1953-1972, September 2026.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

Malaysian Females With Congenital Adrenal Hyperplasia: Surgical Outcomes and Attitudes

Frontiers in Pediatrics, 2019
Background: Girls born with congenital adrenal hyperplasia have virilized external genitalia. There is considerable debate regarding both the outcomes of feminizing genitoplasty and timing of the surgery in this population.Objective: To investigate ...
Ani Amelia Zainuddin, Sonia Regina Grover, Chong Hong Soon, Abdul Ghani Nur Azurah, Zaleha Abdullah Mahdy, Loo Ling Wu, Rahmah Rasat, Fatimah Harun, Wee Yan Chia, Khadijah Shamsuddin   +9 more
doaj   +1 more source