Results 171 to 180 of about 5,719,356 (287)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

World Psychiatric Association perspectives on person-centered psychiatry and medicine

International Journal of Integrated Care, 2010
Juan E. Mezzich
doaj  

Development and Content Validation of a Person-Centered Care Instrument for Healthcare Providers. [PDF]

Nurs Rep
Soriano K, Nakatani S, Onishi K, Ito H, Nakano Y, Takashima Y, Zhao Y, Blaquera AP, Tanioka R, Betriana F, Soriano GP, Yasahura Y, Osaka K, Kataoka M, Miyagawa M, Akaike M, Irahara M, Tanioka T.   +17 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Perceptions of nursing home staff, residents and relatives on the quality of person-centered care in Spain nursing homes across the COVID-19 Pandemic. [PDF]

BMC Geriatr
Moreno-Martin P, Noell-Boix R, Sánchez-Martínez I, Jerez-Roig J, Gómez-Batiste X, March-Amengual JM.   +5 more
europepmc   +1 more source

Recognizing Person-Centered Care [PDF]

Caring for the Ages, 2010
openaire   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

A Bibliometric Review of Person-Centered Care Research 2010-2024. [PDF]

Healthcare (Basel)
Tong LK, Tam HL, Mao AM.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Neurological perspectives on person-centered medicine

International Journal of Integrated Care, 2010
Johan A Aarli
doaj