Results 61 to 70 of about 5,719,356 (287)
Training Doctors for Person-Centered Care
Academic Medicine, 2016 Person-centered care, in which an individual patient's goals and preferences are treated as paramount, should be the standard throughout the nation. Achieving this ideal will require a change in the culture of health care, and medical schools can play a vital role in helping achieve it.
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Person-Centered Integrative Diagnosis and Its Context
, 2017 Diagnosis as a sound understanding of a clinical situation to serve as informational base for clinical care planning is a fundamental activity in medicine.
Robert Cloninger, C +7 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Person-centered health promotion
, 2023 Since the dawn of mankind, ancient civilizations have always engaged a personalized approach to health, and at the same time have utilized a diversity of positive symbols to represent health, including the complementarity of the ying and yang in China ...
Phillips, Susan P. +7 more
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Effects of person-centered care on residents and staff in aged-care facilities: a systematic review
, 2013 Sonya Brownie, Susan NancarrowSchool of Health and Human Sciences, Southern Cross University, Lismore, NSW, AustraliaBackground: Several residential aged-care facilities have replaced the institutional model of care to one that accepts person-centered ...
Nancarrow S, Brownie S
core
People-centered health services
, 2023 People-centered health services (PCHS) is one of the principles of Person Centered Medicine. Such services aim to place persons, people and the community at the center of the care model.
Canchihuaman, Fredy A. +9 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source