Results 111 to 120 of about 180,320 (291)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Person-Centred Palliative Home Care From a Patient and Family Carer Perspective – A Qualitative Interpretive Meta Synthesis

Global Qualitative Nursing Research
With an ageing population and increasing chronic illness, the need for palliative care is growing. Most people prefer to be cared for at home when possible, making it essential to understand the experiences of patients and families receiving care at home
Lotta Pham, Malin Bengtsson, Stina Nyblom, Joakim Öhlén, Jeanette Källstrand   +4 more
doaj   +1 more source

Patient and healthcare professional engagement and time use within a randomised controlled trial: investigating intervention costs associated with remote person-centred care in Sweden

BMJ Open
Objectives To describe the usage patterns of patients and healthcare professionals (HCPs) using a person-centred telehealth and e-health intervention.Design An exploratory, descriptive, observational study embedded in the “Person-centred care at a ...
Hanna Gyllensten, Lilas Ali, Emmelie Barenfeld, Andreas Fors, Inger Ekman, Matilda Cederberg   +5 more
doaj   +1 more source

Purposeful Agency in Support Seeking During Cancer Treatment From a Person-Centered Perspective

Global Qualitative Nursing Research, 2016
People diagnosed with early-stage breast cancer (ESBC) manifest high supportive needs. eHealth supportive programs successfully satisfy those needs, but the process of generating supportive outcomes is less understood.
Filipa Ventura, Ingalill Koinberg, Per Karlsson, Richard Sawatzky, Joakim Öhlén   +4 more
doaj   +1 more source

What is preventing dentists from providing person-centred care?

, 2018
Most healthcare professions have shifted the way they teach clinical approaches from a biomedical to a person-centred perspective. Yet, dentistry remains strongly anchored in a biomedical world.The objective of this project was to understand the barriers
Nareg Apelian, Apelian, Nareg, Bedos, Christophe, Christophe Bedos, Vergnes, Jean-Noel, Jean-Noel Vergnes, Hovey, Richard, Richard Hovey   +7 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Tensions in patient involvement and engagement in health research and development: a qualitative interview study with key actors

Research Involvement and Engagement
Patient involvement and engagement (PIE) is increasingly recognised as essential for improving health research and service design and for supporting the transition toward person-centred healthcare systems.
Kiana Kiani, Vinh Phillips Ingvason Nguyễn, Elin Siira, Catarina Wallengren, Axel Wolf, Ida Björkman   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Same same or different? A review of reviews of person-centred and patient-centred care

, 2019
ObjectiveTo provide a synthesis of already synthesized literature on person-centered care and patient-centered care in order to identify similarities and differences between the two concepts.MethodsA synthesis of reviews was conducted to locate ...
Höglander, Jessica,, Holmström, Inger K,, Condén, Emilie,, Skoglund, Karin,, Summer Merenius, Martina,, Conden, Emelie,, Kumlin, Tomas,, Meranius, Martina Summer,, Sundler, Annelie Johansson,, Summer Meranius, Martina,, Sundler, Annelie J.,, Eklund, Jakob Hakansson,, Kaminsky, Elenor,, Håkansson Eklund, Jakob,, Holmström, Inger K.,   +14 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source