Results 171 to 180 of about 5,403,999 (275)

From policy to person-centred care: insights into the development of complications of excess weight clinics in England. [PDF]

BMC Health Serv Res
Ioannou E, Coulman K, Nobles J, Garside M, Nield L, Davies P, Kinsella K, Ells L, Homer C.   +8 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Remote person-centred care and long-term medication management in primary care: post hoc analysis of a randomised controlled trial. [PDF]

BMJ Open
Mannheimer S, Fors A, Holst A, Gyllensten H.   +3 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Key components in implementation of person-centred care for older people in out-of-hospital settings- An extended abstract of a systematic review -

The aim of the systematic review was to explore the content and essential components of implemented person-centred care in the out-of-hospital context for people aged 65 and older.
Patel, Harshida,, Wijk, Helle,, Ekman, Inger,, Olaya-Contreras, Patricia,, Ebrahimi, Zahra,   +4 more
core  

Developing a tool to advance person-centred care in hospice: The little things are the big things. [PDF]

Palliat Care Soc Pract
Macdonald ME, Salmaniw S, McNeil-Campbell L, D'Intino AF, Sawchuk L, Corbett C, Lawrence L.   +6 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

A multi‑country evaluation of healthcare professionals' experiences with the PanCareFollowUp training package to implement person-centred care in childhood cancer survivorship care: A PanCareFollowUp study. [PDF]

Support Care Cancer
Loonen JJ, Bouwman E, Penson A, Follin C, Uyttebroeck A, Breij D, Kepakova K, Prikken S, Hjorth L, Winther JF, van der Pal HJH, Schneider C, Kienesberger A, Gsell H, Michel G, Pluijm SMF, Skinner R, Kremer LCM, Muraca M, Kepak T, Hermens RPMG, PanCareFollowUp Consortium.   +21 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source