Results 71 to 80 of about 5,403,999 (275)

Building a programme theory of a specialist paediatric palliative and hospice care programme: development process and methodological reflection

BMC Palliative Care
Background Paediatric palliative and hospice care aims to improve the quality of life of children with life-limiting and life-threatening conditions and their families. The number of these patients has risen significantly in recent years, resulting in an
Martin Wallner, Daniela Haselmayer, Martin Nagl-Cupal, Jasmin Eppel-Meichlinger, Hanna Mayer   +4 more
doaj   +1 more source

In the shadow of Graves’ disease: a qualitative interview study of patients’ experiences conducted at a secondary referral centre in Sweden

BMJ Open
Objective Graves’ disease (GD) is the most common form of hyperthyroidism in Sweden with an incidence of 21/100 000 individuals, the majority of whom are women of working age. GD can be overwhelming for the affected patient.
Andreas Fors, Sara Alsén, Agneta Lindo, Helena Filipsson Nyström   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Person-centred care and the work-related health and job satisfaction of health and social care professionals: protocol for a prospective longitudinal cohort study combined with qualitative studies (the PCC@Work project)

BMC Health Services Research
Background The interplay of ethical stress, heavy workloads, and job dissatisfaction poses challenges to both the recruitment and retention of health and social care professionals. Person-centred care, rooted in ethical principles, involves collaborative
Cornelia van Diepen, Qarin Lood, Kristoffer Gustavsson, Malin Axelsson, Monica Bertilsson, Gunnel Hensing, Andreas Fors   +6 more
doaj   +1 more source

Development and validation of an enhanced PERCCI-S (PERCCI-S-Rev) for measuring person-centred home-based primary care

Frontiers in Health Services
BackgroundThe Person-Centred Community Care Inventory – Swedish version (PERCCI-S) has been used in Swedish municipalities to measure person-centred care in home-based primary care (HBPC) from the patient's perspective since 2021.
Theresa Larsen, Theresa Larsen, Theresa Larsen, Theresa Larsen, Richard Sawatzky, Richard Sawatzky, Richard Sawatzky, Helle Wijk, Helle Wijk, Helle Wijk, Helle Wijk, Ewa Wikström, Axel Wolf, Axel Wolf, Axel Wolf   +14 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Bodywork in dementia care: recognising the commonalities of selfhood to facilitate respectful care in institutional settings [PDF]

, 2014
This paper draws on two data sources (Kelly's ethnographic study and a British Broadcasting Corporation television programme) to explore the practice of bodywork in the care of frail people with dementia in institutional settings.
Kelly, Fiona, FIONA KELLY
core   +1 more source