Results 161 to 170 of about 3,422,515 (359)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Telerehabilitation Trends in Australian Physiotherapy and an Exploration of Factors That Influence Use After COVID-19 Restrictions: Qualitative Content Analysis. [PDF]
Ross MH +5 more
europepmc +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Efficient EEG-Based Person Identification: A Unified Framework from Automatic Electrode Selection to Intent Recognition. [PDF]
Pan Y, Dong J, Zhang J.
europepmc +1 more source
Ikke‐overvåket inntak av legemidler for personer i legemiddelassistert rehabilitering
Laila Hov +3 more
openalex +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Dynamic Modeling with Intensive Longitudinal Data: One-Step and Two-Step DSEM Approaches. [PDF]
Wang L, Fang Y, Bergeman CS.
europepmc +1 more source

