Results 181 to 190 of about 1,398,788 (265)

Remote Augmented Reality Versus Traditional Simulation for Team Leader Assessment in a Cardiac Arrest Scenario: Noninferiority Randomized Controlled Trial.

JMIR Med Educ
Gianotto-Oliveira R, Rojas M, Queiroz M, Zanchetta F, Ferrari A, Kojima L, Paula A, Campos B, Cecilio-Fernandes D, Caruso TJ.   +9 more
europepmc   +1 more source

Person-centered practice in the Portuguese healthcare system: A documentary study. [PDF]

PLoS One
Vareta D, Santana E, Oliveira C, Baixinho C, Ventura F.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Does the Use of Crowdsourced Listeners Yield Different Speech Intelligibility Results Than In-Person Listeners for Typically Developing Children? [PDF]

J Speech Lang Hear Res
Salvo HD, Mahr TJ, Sandgren C, Mabie H, Hustad KC.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Maternal Use of Physical Discipline and Children's Externalizing Problems Across Childhood in Singapore. [PDF]

Fam Process
Kyeong Y, Koyama Y, Sudo M, Kee MZL, Chen H, Eriksson JG, Yap FKP, Chong YS, Tiemeier H, Setoh P.   +9 more
europepmc   +1 more source

Personality. Person. Character

European Scientific e-Journal, 2018
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Ecological Momentary Assessment of Person-Reported Outcomes in Diabetes: Unlocking Insights with Continuous Glucose Monitoring and the Potential for Precision Medicine. [PDF]

Curr Diab Rep
Ehrmann D, Hermanns N, Schmitt A, Klinker LY, Kulzer B.   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source