Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
A Multi-Attention Approach for Person Re-Identification Using Deep Learning. [PDF]
Saber S+4 more
europepmc +1 more source
Swiss-System Based Cascade Ranking for Gait-Based Person Re-Identification
Wei Lan+3 more
openalex +2 more sources
Deep Hybrid Similarity Learning for Person Re-Identification [PDF]
Jianqing Zhu+5 more
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Joint Modal Alignment and Feature Enhancement for Visible-Infrared Person Re-Identification. [PDF]
Lin R, Wang R, Zhang W, Wu A, Bi Y.
europepmc +1 more source
Regularized Bayesian Metric Learning for Person Re-identification
Venice Erin Liong, Jiwen Lu, Yongxin Ge
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Person Re-Identification with RGB-D and RGB-IR Sensors: A Comprehensive Survey. [PDF]
Uddin MK+4 more
europepmc +1 more source
Unified Framework for Automated Person Re-identification and Camera Network Topology Inference in Camera Networks [PDF]
Yeong-Jun Cho+4 more
openalex +1 more source