Results 111 to 120 of about 2,278,305 (352)
Emergency Preparedness for Older People [PDF]
After the 9/11 World Trade Center attacks, a large population of older persona and people with disabilities living near the disaster area were left stranded in their homes without assistance.
Nora O'Brien
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
[Review of] Luci Tapahonso. Saanii Dahataal, The Women Are Singing: Poems and Stories [PDF]
Wrapped around the cover of this volume is a painting by Emmi Whitehorse entitled, White Shell Woman Story 111. This is an implication of Tapahonso’s Navajo origins -- mythical, historical, and persona -- which are evident throughout the book.
McNeil, Elizabeth
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Este artigo propõe analisar as ações políticas e sociais adotadas em tempos pandêmicos, estabelecendo para tanto um paralelo entre epidemia da AIDS e, recentemente, a pandemia do novo coronavírus, COVID - 19.
Emerson Persona, Luciana Martha Silveira
doaj +1 more source
Background: Trauma-focused treatments (TFTs) for patients with post-traumatic stress disorder (PTSD) are highly effective, yet underused by therapists.Objective: To describe a new way of implementing (adequate use of) TFTs, using a therapist rotation ...
Agnes Van Minnen +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

