Patient personas of delayed healthcare-seeking behavior among patients with breast cancer-related lymphedema: A qualitative study. [PDF]
Wang L +7 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Large Language Model-Based Chatbots and Agentic AI for Mental Health Counseling: Systematic Review of Methodologies, Evaluation Frameworks, and Ethical Safeguards. [PDF]
Cho HN, Wang J, Hu D, Zheng K.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The Patient Persona of the Self-Management Experience of Home-Based Rehabilitation for Spinal Cord Injury Patients: A Qualitative Study [Letter]. [PDF]
Liu X, Ning L.
europepmc +1 more source
Personas que conectan con personas :
En Publicidad y Relaciones Públicas, no basta con saber comunicar; hay que conectar. La Inteligencia Emocional es una competencia clave en este ámbito, pero su enseñanza sigue siendo una asignatura pendiente en la universidad. Para abordar esta carencia, se diseña un manual educativo que integra la Inteligencia Emocional como una competencia esencial ...
openaire +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Factors influencing invasive arterial blood pressure monitoring accuracy: a qualitative study using the i-PARIHS framework and personas. [PDF]
Yu M +8 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Praxis function in the ADL Observation Scale: Spanish cross-cultural adaptation and psychometric properties. [PDF]
Sánchez-Bermejo L +2 more
europepmc +1 more source

