Results 171 to 180 of about 2,278,305 (352)

Aspectos psicológicos a tener en cuenta en la atención de víctimas de la trata de personas [PDF]

, 2017
Nicolás Chahín-Pinzón, Johana Marcela Reyes Jaimes, Jakeline Vargas Parra   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Digital interventions addressing the unmet needs of older adults with multimorbidity: a mixed-methods persona design approach. [PDF]

Front Public Health
De Luca V, Virgolesi M, Cuomo A, Lemmo D, Perillo M, Canfora F, Aprano S, Mezza F, Vetrani C, Freda MF, Adamo D, Rea T, Mercurio L, Attaianese E, Menditto E, Colao A, Iaccarino G, Illario M.   +17 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Reply to Girard <i>et al.</i>: Lung Ultrasound Elastography: New Tools to Personalize Mechanical Ventilation. [PDF]

Am J Respir Crit Care Med
Persona P, Zarantonello F, Pettenuzzo T, Navalesi P.   +3 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Explainable AI-driven precision clinical trial enrichment: demonstration of the NetraAI platform with a phase II depression trial. [PDF]

NPJ Digit Med
Geraci J, Qorri B, Tsay M, Cumbaa C, Leonczyk P, Alphs L, Ballard ED, Zarate CA, Pani L.   +8 more
europepmc   +1 more source

Presentación [PDF]

, 2012
Persona-y-Derecho
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Drug screening in human plasma by cloud-point extraction and HPLC

Open Chemistry, 2013
Madej Katarzyna, Persona Karolina
doaj   +1 more source