Results 171 to 180 of about 2,337,590 (401)
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston+7 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
[Review of] Luci Tapahonso. Saanii Dahataal, The Women Are Singing: Poems and Stories [PDF]
Wrapped around the cover of this volume is a painting by Emmi Whitehorse entitled, White Shell Woman Story 111. This is an implication of Tapahonso’s Navajo origins -- mythical, historical, and persona -- which are evident throughout the book.
McNeil, Elizabeth
core +1 more source
Exploring Changes in Nation Perception with Nationality-Assigned Personas in LLMs [PDF]
Persona assignment has become a common strategy for customizing LLM use to particular tasks and contexts. In this study, we explore how evaluation of different nations change when LLMs are assigned specific nationality personas. We assign 193 different nationality personas (e.g., an American person) to four LLMs and examine how the LLM evaluations (or '
arxiv
Cerebro, persona e identidad [PDF]
Las neurociencias, en su breve recorrido histórico, valorizan cada vez más el cerebro como el órgano en que se hallan concentradas todas aquellas características que nos permiten considerarnos seres humanos.
Ricci, Ricardo Teodoro
core
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
The place of trauma in the treatment of personality disorders [PDF]
Theo J. M. Ingenhoven
doaj +1 more source
Helpful assistant or fruitful facilitator? Investigating how personas affect language model behavior [PDF]
One way to personalize and steer generations from large language models (LLM) is to assign a persona: a role that describes how the user expects the LLM to behave (e.g., a helpful assistant, a teacher, a woman). This paper investigates how personas affect diverse aspects of model behavior.
arxiv