Results 171 to 180 of about 104,754 (312)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Innovative approach to designing user-centred digital solutions for plastic surgery patients with non-melanoma skin cancer. [PDF]

Front Public Health
Cavaliere A, De Luca V, Virgolesi M, Iaccarino G, Mercurio L, Illario M, Schonauer F.   +6 more
europepmc   +1 more source

Proyecto: Cappaz. Bolsa de trabajo específica para personas con discapacidad

, 2017
Mirko Daniel Del Castillo Andia, Jacqueline Ysabel Luyo Lozano, José Fernando Silva Galindo, Belu Jhansini Gamboa Quispe   +3 more
openalex   +1 more source

Los "otros profesionales" en la atención a personas con depresión: psicólogos, trabajadores sociales y enfermeras

, 2013
Laura Balagué Gea, Carlos Calderón Gómez, Ander Retolaza Balsategui, Amaia Bacigalupe, Janire Payo Gordón, Isabel Mosquera   +5 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Tailored professional identity personas of male undergraduate nursing students: a secondary analysis of qualitative data. [PDF]

BMC Nurs
Han X, Duan Y, Hong S, Yu Y, Hao P, Chen Y.   +5 more
europepmc   +1 more source

Consideraciones jurídicas sobre las migraciones en Cuba. Una propuesta para la regulación de los delitos de trata y tráfico de personas / Legal considerations on migrations in Cuba. A proposal for the regulation of human trafficking and migrant smuggling crimes

, 2018
Laidiana Torres Rodríguez, Lisett D. Páez Cuba   +1 more
openalex   +1 more source

La discapacidad en las estadísticas del Impuesto sobre la Renta de las Personas Físicas

, 2016
Domingo Carbajo Vasco
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source