Results 351 to 360 of about 2,337,590 (401)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Management of Femoral Condyle Insufficiency Fractures Following Total Knee Arthroplasty (FCIF-TKA). [PDF]

Cureus
Wong WS, Chen H, Lim JW, Siow WM, Poon KB.   +4 more
europepmc   +1 more source

[Beliefs of primary care professionals regarding people with suicidal behavior: A qualitative study]. [PDF]

Aten Primaria
Dois Castellón A, Inostroza Ortega T.
europepmc   +1 more source

'Changing the Focus': Co-Design of a Novel Approach for Engaging People with Dementia in Physical Activity. [PDF]

Nurs Rep
Meyer C, Lee DA, Callisaya M, Taylor ME, Lawler K, Levinger P, Hunter S, Mackey DC, Burton E, Brusco N, Haines T, Ekegren CL, Crabtree A, Hill KD.   +13 more
europepmc   +1 more source

How can measurement-based care improve psychotherapy processes and mental health service delivery? A synthesis of expert perspectives. [PDF]

World Psychiatry
Moltu C, van Sonsbeek M, Bovendeerd B, de Jong K, Barkham M, Sales C, McAleavey A, Mellor-Clark J, Schwartz B, Nordberg SS, Jacob J, Lutz W, Kaldo V, Janse P, Brattland H, Compare A, Douglas S.   +16 more
europepmc   +1 more source

Six personas to adopt when framing theoretical research questions in biology. [PDF]

Proc Biol Sci
Shaw AK, Bisesi AT, Wojan C, Kim D, Torstenson M, Naven Narayanan, Lutz P, Ales R, Shao C.   +8 more
europepmc   +1 more source

Representing the Needs of Rural Caregivers of People Living With Alzheimer's Disease and Related Dementias Through User Personas. [PDF]

Innov Aging
Jolliff A, Hill JR, Zuraw M, Elliott C, Werner NE.   +4 more
europepmc   +1 more source

RETRACTION: lncRNA‐PDPK2P Promotes Hepatocellular Carcinoma Progression Through the PDK1/AKT/Caspase 3 Pathway

Molecular Oncology, EarlyView.
RETRACTION: W. Pan, W. Li, J. Zhao, Z. Huang, J. Zhao, S. Chen, C. Wang, Y. Xue, F. Huang, Q. Fang, J. Wang, D. Brand, and S. G. Zheng, “lncRNA‐PDPK2P Promotes Hepatocellular Carcinoma Progression Through the PDK1/AKT/Caspase 3 Pathway,” Molecular Oncology 13, no. 10 (2019): 2246–2258, https://doi.org/10.1002/1878-0261.12553.
wiley   +1 more source

Guía Docente de la Asignatura de Medicina Familiar y Comunitaria para ser incluida en los Planes de Estudios de las Facultades de Medicina Españolas. [PDF]

Aten Primaria
europepmc   +1 more source