Results 231 to 240 of about 27,444,501 (283)

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

open access: yesAdvanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang   +10 more
wiley   +1 more source

Osseoperceptive EMG Feedback Improves Grasp Force Control in Myoelectric Prosthetic Hands

open access: yesAdvanced Science, EarlyView.
Osseoperception is explored as a non‐invasive pathway for delivering sensory feedback in myoelectric prosthetic control. By encoding the user's electromyographic (EMG) signal through bone‐conducted stimulation, this approach enables predictive grasp force regulation.
Cristian Felipe Blanco‐Diaz   +2 more
wiley   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

open access: yesAdvanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen   +6 more
wiley   +1 more source

Functional–Taxonomic Scaling Resolves Conflicting Average Genome Size Estimates Across Environmental Gradients

open access: yesAdvanced Science, EarlyView.
Based on genome size‐functional breadth theory, we introduce and validate a framework that adjudicates conflicting average genome size (AGS) estimates by testing which estimate yields a gap between scaled functional diversity and scaled taxonomic diversity that is consistent with the expected positive association between genome size and gene functional
Huanhuan Zhu   +8 more
wiley   +1 more source
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The Personal Data Store Approach to Personal Data Security

IEEE Security & Privacy, 2013
A growing number of actors believe personal data stores (PDSs) are the solution to the issue of online privacy. With PDSs, people can choose to share specific personal information or restrict access to certain interested parties. A small-scale test involving job applicants and employers attempted to ascertain the extent to which users are willing to ...
Tom Kirkham   +3 more
openaire   +1 more source

Code as Personal Data

SSRN Electronic Journal, 2021
This paper argues that, besides information that is conventionally seen as ‘personal data’, software increasingly displays characteristics of what constitutes ‘personal data’ in the sense of European data protection law. Therefore, certain types of, and even all software, with some caveats, may fall within the material scope of the GDPR already, and ...
openaire   +2 more sources

Personal data vaults

Proceedings of the 6th International COnference, 2010
The increasing ubiquity of the mobile phone is creating many opportunities for personal context sensing, and will result in massive databases of individuals' sensitive information incorporating locations, movements, images, text annotations, and even health data.
Min Y. Mun   +7 more
openaire   +1 more source

Gifting Interpretations of Personal Data

Extended Abstracts of the 2018 CHI Conference on Human Factors in Computing Systems, 2018
Research on physical representations of data has often used personal data as its focus. Core aim of making personal data physical is to provoke self-reflections through a felt experience. In this paper, we present a preliminary study which employs the idea of gift-giving as a means to explore one's online data.
Maria Karyda 0002   +2 more
openaire   +2 more sources

Personal Data, Non-personal Data, Anonymised Data, Pseudonymised Data, De-identified Data

2021
The primary scope of application of the General Data Protection Regulation—Regulation (UE) 2016/679 (GDPR)—is ‘personal data’; ‘data’ that is not personal data can be freely processed within the legal framework of the Regulation (UE) 2018/1807. Although the European data protection framework recognises these two categories of data—‘personal data’ and ...
openaire   +2 more sources

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