Results 31 to 40 of about 276,346 (306)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Personal and Family Names of Orthodox Clergymen and Members of Their Families in the 18th Century (with Reference to the Clergy of Rzhev and Ostashkov Cities) [PDF]

open access: yesВопросы ономастики, 2014
The article deals with the personal and family names of clergymen of two cities of Tver eparchy, Rzhev and Ostashkov, in the 18th century, the analyzed materials being retrieved from state archives (materials of censuses of clergymen and documents of ...
Andrey V. Matison
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Contribution to the Study of the Reflection of the Saint’s Name Ivan in Croatian Anthroponimy

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2009
This paper tries to give an overview of the many various reflections of he saint’s name John in the Croatian anthroponimic system. The authorfocuses on the area of south Dalmatia (including Boka kotorska) and Donja Hercegovina.
Domagoj Vidović
doaj  

Frekwencja, struktura i budowa słowotwórcza pochodnych imion osobowych występujących w funkcji zoonimów

open access: yesStudia z Filologii Polskiej i Słowiańskiej
Frequency, Structure and Word-Formation Patterns of Derivatives of Personal Names Used as Zoonyms The article is a continuation of earlier analyses of the material excerpted from a database containing a list of zoonyms in one of the veterinary clinics
Agnieszka Kijak
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Revisiting the Paronymic Attraction to a Personal Name: the Name Elena in Russian Dialects [PDF]

open access: yesВопросы ономастики, 2019
The article focuses on Russian dialectal words, which are full homonyms of the name Elena or its derivatives (Alyona, Alyonka, Elenka, Lena, Lenka) included into the same morphosemantic field.
Lyubov A. Feoktistova
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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