Results 51 to 60 of about 3,145,972 (324)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Personal and ethical components of the engineer in the 21st century [PDF]

open access: yesSHS Web of Conferences, 2019
The article studies personal components of a modern engineer who is a key figure in the Russian and global space.The vector of thinking, ethical priorities, reflective positions and identities determine the way to find a techno-humanitarian balance as a ...
Potamskaya V.P.   +2 more
doaj   +1 more source

Immigrant women’s entrepreneurship: is there a development model in Italy? [PDF]

open access: yes, 2017
The aim of this paper is to verify if there is a typical enterprise model for the development of immigrant female entrepreneurship in Italy. Based on the literature on the subject, however, it is useful to ask the following research question: “can ...
Paoloni, Mauro   +2 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Factor Structure of the AUDIM-M Dimensional Self-Concept Questionnaire in Mexican Adolescents

open access: yesChildren, 2022
Self-concept is one of the most relevant variables in the field of personality, and a negative self-perception can pose a risk to the adolescent’s development.
José René Blanco   +7 more
doaj   +1 more source

On the grammar of politics—or why conservatives prefer nouns [PDF]

open access: yes, 2016
Previous research indicates that political conservatism is associated with epistemic needs for structure and certainty (Jost et al., 2003) and that nouns elicit clearer and more definite perceptions of reality than other parts of speech (Carnaghi et al.,
Abe   +64 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Sense of control and aging self-stereotyping: the role of need for structure

open access: yesBMC Psychology
The current study involved two experiments that examined the relationships between lack of control, need for structure, and self-stereotyping in older adults.
Qingxiu Dang, Baoshan Zhang
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

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