Results 211 to 220 of about 22,687 (246)

Multitask Deep Learning Model for Predicting Lymph Node Metastasis and Disease‐Free Survival From Cytology Images in Bladder Cancer: A Multicenter Study With Pan‐Cytology Validation

Advanced Science, EarlyView.
Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Guibin Hong, Fan Jiang, Ye Xie, Xiaowei Huang, Runnan Shen, Yun Wang, Mengyi Zhu, Haoxuan Wang, Hongkun Yang, Yanxiao Nie, Zhen Lin, Rui Chen, Nengtai Ouyang, Tianxin Lin, Shaoxu Wu   +14 more
wiley   +1 more source

Developing Transdiagnostic Single-Session Interventions for University Students Experiencing Disordered Eating: A Mixed-Method Co-Design Study. [PDF]

Int J Eat Disord
Jabs M, Wade TD.
europepmc   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Personalised care, youth mental health, and digital technology: A value sensitive design perspective and framework. [PDF]

Ethics Inf Technol
Poulsen A, Hickie IB, Chong MK, LaMonica HM, Turner A, Iorfino F.   +5 more
europepmc   +1 more source

Integrating Artificial Intelligence with Gamification in Medical Education: A Pedagogically Grounded Framework and Critical Review. [PDF]

Adv Med Educ Pract
Bharatha A, Ojeh N, Campbell MH, Krishnamurthy K, Sangishetti VP, Bhuvanagiri L, Gupta S, Rahman S, Reddy S, Majumder MAA.   +9 more
europepmc   +1 more source

A multimodal, risk-stratified framework for AI-driven early risk prediction and personalised prevention in obesity. [PDF]

Front Artif Intell
Zhao S, Cheang C, Lin J, Mio W, Che S, Kuok K.   +5 more
europepmc   +1 more source

User experience and perceived impact of the Eating Disorder Support App: a mixed-methods evaluation. [PDF]

J Eat Disord
Rysinova V, Ramsey-Wade CE, Trippick C, Norweg S.   +3 more
europepmc   +1 more source