Results 51 to 60 of about 915,053 (362)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

open access: yesMolecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger   +2 more
wiley   +1 more source

Sequential Transformer for End-to-End Person Search [PDF]

open access: yesarXiv, 2022
Person Search aims to simultaneously localize and recognize a target person from realistic and uncropped gallery images. One major challenge of person search comes from the contradictory goals of the two sub-tasks, i.e., person detection focuses on finding the commonness of all persons so as to distinguish persons from the background, while person re ...
arxiv  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Identifying and Manipulating the Personality Traits of Language Models [PDF]

open access: yesarXiv, 2022
Psychology research has long explored aspects of human personality such as extroversion, agreeableness and emotional stability. Categorizations like the `Big Five' personality traits are commonly used to assess and diagnose personality types. In this work, we explore the question of whether the perceived personality in language models is exhibited ...
arxiv  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

The validation of the English Impostor-Profile 30 and the exploratory formulation of the learned helplessness model of the impostor phenomenon

open access: yesActa Psychologica, 2022
The learned helplessness model of the Impostor Phenomenon is an exploratory approach to explain the Impostor Phenomenon by linking the constructs of growth mindset, learned helplessness, grit, thought-action fusion, and defensive pessimism. In this study,
Fabio Ibrahim   +2 more
doaj  

Learning Person-specific Network Representation for Apparent Personality Traits Recognition [PDF]

open access: yesarXiv, 2023
Recent studies show that apparent personality traits can be reflected from human facial behavior dynamics. However, most existing methods can only encode single-scale short-term facial behaviors in the latent features for personality recognition. In this paper, we propose to recognize apparent personality recognition approach which first trains a ...
arxiv  

An open chat with…Pierre Santucci: a testimonial on why we should engage with scientific societies and their journals

open access: yesFEBS Open Bio, EarlyView.
Pierre SANTUCCI is a principal investigator at the CNRS—Aix Marseille Université and recipient of a FEBS Excellence Award. He was also recently appointed FEBS Open Bio Publishing Liaison Officer. In this Open Chat with…, he discusses the importance of engaging with scientific societies and their journals, and highlights through some of his personal ...
Pierre Santucci, Ioannis Tsagakis
wiley   +1 more source

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