Results 81 to 90 of about 2,328,427 (310)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Promising Subjective and Objective Benefits of Modified Mindfulness-Based Stress Reduction Training for Chinese Adults with Chronic Pain: A Pilot Randomized Control Study

open access: yesPain and Therapy, 2023
Introduction Mindfulness-based stress reduction (MBSR) has demonstrated its effectiveness in reducing pain-related stress in adults with chronic pain. However, the implementation of MBSR needs modifications across cultures.
Shuanghong Chen   +9 more
doaj   +1 more source

TEST OF PERSONAL INTELLIGENCE 1.4 (TOPI 1.4) MANUAL [PDF]

open access: yes, 2014
Personal intelligence involves the capacity to reason about personality and personality-relevant information. People high in personal intelligence are good at understanding themselves and others.
Caruso, David R.   +2 more
core   +1 more source

Medication overuse headache, addiction and personality pathology: a controlled study by SWAP-200 [PDF]

open access: yes, 2019
Background: Medication Overuse Headache (MOH) is a type of chronic headache, whose mechanisms are still unknown. Some empirical investigations examining the addiction-like behaviors and processes, as well as personality characteristics underlying MOH ...
Cristofalo, Patrizia   +8 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Cognitive Investments in Academic Success: The Role of Need for Cognition at University

open access: yesFrontiers in Psychology, 2017
Previous research has shown that Need for Cognition (NFC), the individual tendency to engage in and enjoy cognitive endeavors, contributes to academic performance.
Julia Grass   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Big Five, Mindfulness, and Psychological Well-being

open access: yes, 2018
How do personality variables and mindfulness relate to psychological well-being? Research relates personality variables and psychological well-being and distress (as in depression, anxiety and stress); and mindfulness and psychological well-being ...
Hicks, Richard E., Mehta, Yukti
core   +1 more source

How do you say ‘hello’? Personality impressions from brief novel voices [PDF]

open access: yes, 2014
On hearing a novel voice, listeners readily form personality impressions of that speaker. Accurate or not, these impressions are known to affect subsequent interactions; yet the underlying psychological and acoustical bases remain poorly understood ...
A Todorov   +103 more
core   +5 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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