Results 151 to 160 of about 5,871,341 (301)

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance

Advanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao, Guangdi Chu, Wei Jiao, Yuchuan Zhong, Hang Yuan, Chengjun Li, Jinhua Li, Shuxin Wang, Bo Guan, Jianchang Zhao, Lizhi Pan, Haitao Niu, Jianmin Li   +12 more
wiley   +1 more source

A Brief but Comprehensive Review of Research on the Alternative DSM-5 Model for Personality Disorders

Current Psychiatry Reports, 2019
Johannes Zimmermann, André Kerber, Katharina Rek, C. Hopwood, R. Krueger   +4 more
semanticscholar   +1 more source

Self-Knowledge in Personality Disorders: An Emotion-Focused Perspective

, 2018
Emotional knowledge about one's own and others’ emotional experience are central features of mental health and may be characteristic of therapeutic processes leading to good outcome.
Antonio Pascual-Leone, Kramer, U., Ueli Kramer, Pascual-Leone, A., Kramer U, Pascual-Leone A   +5 more
core   +1 more source

Atomically Dispersed Fe‐Modified SnS for Sn‐Centered Peroxymonosulfate Activation Toward Acetaminophen Degradation

Advanced Science, EarlyView.
Atomically dispersed Fe regulates the local electronic environment and surface properties of SnS, while PMS preferentially coordinates to Sn through Sn–O interaction. Fe incorporation further enhances the Sn–OPMS interfacial interaction, facilitating Sn‐centered PMS activation and the generation of SO4•−/•OH for APAP degradation, thereby clarifying the
Shuhui Liu, Yantao Wang, Ya Liu, Jingkai Lin, Shaobin Wang, Wenjie Tian   +5 more
wiley   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

The role of rule-governed behavior in histrionic and compulsive personality disorders [PDF]

, 1987
Behavioral descriptions of the histrionic and compulsive personality disorders as well as cognitive and bio-social learning theories of these disorders appear to be consistent with the hypothesis that these disorders might be related to dysfunctional ...
NC DOCKS at The University of North Carolina at Greensboro, Schneidmiller, Sara Weber   +1 more
core  

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Heterointerface Seeding Accelerates Bi0/Bi3+ Phase Conversion for Ultrafast Aqueous Alkaline Batteries

Advanced Science, EarlyView.
An N‐doped carbon‐confined Bi/Bi2O3 heterostructure enables ultrafast and reversible Bi0/Bi3+ phase conversion through heterointerface seeding. The pre‐established Bi/Bi2O3 interfaces provide nucleation‐active sites for heterophase regrowth, while the N‐C shell promotes electron transport and structural stability, overcoming kinetic limitations in ...
Jingwen Ma, Teng Wang, Jiaye Ye, Tong Yang, Zhongguo Zhao, Yuanyou Peng, Meimei Yu, Chaojiang Fan, Wenhu Li, Hongxia Wang   +9 more
wiley   +1 more source

Stretchable h‐BN/TPU Fibers for Passive‐Active Dual‐Mode Thermal Management and Wearable Haptic Interfaces

Advanced Science, EarlyView.
Optimized 30 wt.% h‐BN/TPU fibers create a thermal conductivity of 2.08 W·m−1·K−1 while retaining mechanical compliance (422% elongation at break). Woven fabrics reduce surface temperature by 5.7°C under simulated solar irradiation. Glove integration enables localized fingertip heating at 29.55°C·s−1 with a thermal relaxation time of approximately 20 s.
Yiwei Zhou, Shanshan Long, Bo Chen, Maohua Li, Linhong Li, Yue Qin, Rongjie Yang, Hanxi Chen, Cheng‐Te Lin, Yixiang Xu, Kean How Cheah, Nan Jiang, Jinhong Yu   +12 more
wiley   +1 more source