Results 41 to 50 of about 541,321 (336)

Understanding obsessive-compulsive personality disorder in adolescence: a dimensional personality perspective [PDF]

, 2010
The validity of the Axis II Obsessive-Compulsive Personality Disorder (OCPD) category and its position within the Cluster C personality disorder (PDs) section of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, APA, 2000) continues to ...
Aelterman, Nathalie, De Fruyt, Filip, Decuyper, Mieke   +2 more
core   +2 more sources

Impulsive traits and 5-HT2A receptor promoter polymorphism in alcohol dependents: Possible association but no influence of personality disorders [PDF]

, 2001
Objective: Impulsive behavior in alcoholics puts them at serious risk of severer course of disease and has been related to the serotonergic neurotransmission dysfunction.
Bahlmann, Miriam, Bondy, Brigitta, Koller, G., Preuss, Ulrich W., Soyka, Michael   +4 more
core   +1 more source

Recognition and management of auditory verbal hallucinations in borderline personality disorder

Frontiers in Psychiatry
BackgroundAuditory verbal hallucinations (AVH) are experienced by 25% of all people diagnosed with a borderline personality disorder. Since the impact of these hallucinations is often substantial, we asked ourselves how often they are discussed in ...
M. B. A. Niemantsverdriet, M. B. A. Niemantsverdriet, C. W. Slotema, C. W. Slotema, I. H. A. Franken, J. Brandsma, M. J. P. M. Verbraak, M. L. Deen, J. D. Blom, J. D. Blom, J. D. Blom, M. Van der Gaag   +11 more
doaj   +1 more source

Self-disgust in patients with borderline personality disorder. The associations with alexithymia, emotion dysregulation, and comorbid psychopathology

Borderline Personality Disorder and Emotion Dysregulation, 2023
Background Self-disgust is a negative self-conscious emotion, which has been linked with borderline personality disorder (BPD). However, it has not yet been investigated in relation to both emotion dysregulation and alexithymia, which are recognized as ...
Emilia Kot, Barbara Kostecka, Joanna Radoszewska, Katarzyna Kucharska   +3 more
doaj   +1 more source

Hierarchical structure of maladaptive personality traits in older adults: joint factor analysis of the PID-5 and the DAPP-BQ [PDF]

, 2014
In DSM-5, the categorical model and criteria for the 10 personality disorders included in DSM-IV will be reprinted in Section II. Moreover, an alternative dimensional classification model will appear in Section III.
Bastiaansen, Leen, De Clercq, Barbara, Dierckx, Eva, Hofmans, Joeri, Rossi, Gina, Van den Broeck, Joke   +5 more
core   +1 more source

The Association Between Concentrations of Arginine, Ornithine, Citrulline and Major Depressive Disorder: A Meta-Analysis

Frontiers in Psychiatry, 2021
Alterations in the peripheral (e.g., serum, plasma, platelet) concentrations of arginine and its related catabolic products (i.e., ornithine, citrulline) in the urea and nitric oxide cycles have been reported to be associated with major depressive ...
Mingyue Fan, Xiao Gao, Xiao Gao, Li Li, Zhongyu Ren, Leanna M. W. Lui, Roger S. McIntyre, Kayla M. Teopiz, Peng Deng, Bing Cao, Bing Cao   +10 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Personality traits and disorders in childhood. Clinical evaluation and diagnosis [PDF]

, 2018
Objective: aim of the paper is to examine the controversial issue of personality traits and disorders in childhood. Method: a literature review of clinical and research data was performed, and a conceptual synthesis was proposed.
Alexandro Fortunato, Anna Maria Speranza
core  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

Trials
Background Although clinical guidelines prioritize the treatment of depression and anxiety in young persons, there is accumulating evidence that the presence of symptoms of borderline personality disorder (BPD) is associated with the limited ...
Melissa G. A. Remeeus, Sharon L. Clarke, Dine J. Feenstra, Hester Van Eeren, Maaike L. Smits, Sara Debruyne, Mirjam E. J. Kouijzer, Patrick Luyten, Ron H. J. Scholte, Joost Hutsebaut   +9 more
doaj   +1 more source