Results 171 to 180 of about 606,014 (298)

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

open access: yesAdvanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong   +20 more
wiley   +1 more source

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

open access: yesAdvanced Science, EarlyView.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu   +11 more
wiley   +1 more source

Neural Patterns of Social Pain in the Brain‐Wide Representations Across Social Contexts

open access: yesAdvanced Science, EarlyView.
Empathy arises from both physiological and social pain, yet their shared and context‐specific neural mechanisms remain unclear. Combining fMRI and multivariate pattern analysis, this study decodes overlapping empathy networks and distinct representations for social exclusion versus separation.
Xiaodong Zhang   +11 more
wiley   +1 more source

Multimethod investigation of interpersonal functioning in borderline personality disorder. [PDF]

open access: green, 2010
Stephanie D. Stepp   +3 more
openalex   +1 more source

Personality functioning and the pathogenic effect of childhood maltreatment in a high-risk sample. [PDF]

open access: yesChild Adolesc Psychiatry Ment Health, 2022
d'Huart D   +6 more
europepmc   +1 more source

DAPK3 is Essential for DBP‐Induced Autophagy of Mouse Leydig Cells

open access: yesAdvanced Science, EarlyView.
This study has confirmed that death‐associated protein kinase 3 (DAPK3) is essential for dibutyl phthalate (DBP)‐induced autophagy of mouse Leydig cells, and is regulated by both transcription factor specific protein 2 (Sp2) and parkin RBR E3 ubiquitin‐protein ligase (PRKN), and melatonin can alleviate DBP‐induced autophagy of the cells.
Si Yang   +4 more
wiley   +1 more source

Assessment of personality functioning in psychosomatic medicine. [PDF]

open access: yesWien Klin Wochenschr, 2022
Wagner-Skacel J   +4 more
europepmc   +1 more source

High‐Fidelity Computational Microscopy via Feature‐Domain Phase Retrieval

open access: yesAdvanced Science, EarlyView.
An innovative phase retrieval framework, termed FD‐PR, is uniquely established in the image's feature domain through the feature‐extracted, physical‐driven regression with interfaces for combining physics and image processing constraints. FD‐PR takes advantage of invariance components of an image against presences of model mismatch and uncertainty ...
Shuhe Zhang   +4 more
wiley   +1 more source

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