Results 51 to 60 of about 606,014 (298)

Transdiagnostic Mechanisms of Mental Health During the COVID-19 Pandemic on Adults and Families in Germany: Study Protocol of a Cross-Sectional and 1-Year Longitudinal Study

Frontiers in Psychology, 2021
Background: Since the outbreak of COVID-19 pandemic, psychological distress is increased. Transdiagnostic mechanisms, including trauma, personality functioning, mentalizing and emotion regulation are considered relevant to the development and maintenance
Jana Volkert, Jana Volkert, Svenja Taubner, Anna Berning, Laura Kling, Hannah Wießner, Anna K. Georg, Julia Holl   +7 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Does loneliness lie within? Personality functioning shapes loneliness and mental distress in a representative population sample

Journal of Affective Disorders Reports, 2023
Background: Loneliness is a major public health issue and the identification of risk factors is crucial for prevention and intervention. While previous research has often investigated sociodemographic and external factors (e.g., living situation ...
M. Ernst, E. Brähler, J. Kruse, H. Kampling, M.E. Beutel   +4 more
doaj  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Friendship functions and personality traits [PDF]

Psihologija, 2009
The goal of our study was exploration of the factor structure of the MFQ-FF inventory on a sample from Serbian population, and the relations of measures from this inventory (friendship functions) with personality traits, as operationalized by the seven factor model proposed by Tellegen and Waller.
Jelena Zeleskov-Djoric, Ivana Pedovic, Vladimir Hedrih   +2 more
openaire   +2 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Risk Factors for Adult Depression: Adverse Childhood Experiences and Personality Functioning

Frontiers in Psychology, 2020
Background: Depressive disorder is one of the main health problems worldwide. Many risk factors have been associated with this pathology. However, while the association between risks factors and adult depression is well established, the mechanisms behind
Paula Dagnino, Paula Dagnino, Paula Dagnino, María José Ugarte, Felipe Morales, Sofia González, Daniela Saralegui, Johannes C. Ehrenthal   +7 more
doaj   +1 more source

Level of personality functioning and its relationship with core schemas in anxiety and mood disorders

Mediterranean Journal of Clinical Psychology, 2022
Background: The DSM-5 Alternative model for personality disorders initiated a growing body of research on deficits in self-functioning and interpersonal relatedness.
Katerina Naumova, Florijan Naumov
doaj   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Role of Personality Functioning in Predicting Interpersonal and Emotional Problems

Journal of Mazandaran University of Medical Sciences, 2020
Background and purpose: Personality functioning impairment (criterion A) is considered as one of the two essential criteria for diagnosing personality disorders in DSM-5.
Leila Zaeimzadeh, Mozhgan Lotfi, Mahdi Amini   +2 more
doaj