Results 81 to 90 of about 599,850 (287)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Personality functioning and the pathogenic effect of childhood maltreatment in a high-risk sample

Child and Adolescent Psychiatry and Mental Health, 2022
Background While the psychopathological sequalae of childhood maltreatment are widely acknowledged, less is known about the underlying pathways by which childhood maltreatment might lead to an increased risk for mental health problems.
Delfine d’Huart, Joost Hutsebaut, Süheyla Seker, Marc Schmid, Klaus Schmeck, David Bürgin, Cyril Boonmann   +6 more
doaj   +1 more source

Logical reasoning in schizotypal personality [PDF]

, 2004
It was examined whether psychotic-like personality traits in a sample of 205 college students could predict logical reasoning deficits, akin to those seen in schizophrenia.
Tsakanikos, Elias
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Sex differences in personality dysfunction in help-seeking adolescents

Borderline Personality Disorder and Emotion Dysregulation
Introduction Understanding sex differences is crucial for improving diagnosis and treatment for personality disorders (PDs). This study aimed to investigate sex differences in personality dysfunction as per Criterion A of the DSM-5 Alternative Model of ...
Marialuisa Cavelti, Jana Schenk, Silvano Sele, Corinna Reichl, Julian Koenig, Ines Mürner-Lavanchy, Michael Kaess   +6 more
doaj   +1 more source

Relationship Between Personality Disorders Scales, Pathological Personality Traits, and Six Domains of Functioning in Sample With Alcohol Use Disorder

Frontiers in Psychiatry, 2020
BackgroundStudies reveal a functional impairment in patients with personality disorders (PDs), but there is not enough information to form conclusions about this relation in patients with alcohol use disorder (AUD).
Jeļena Koļesņikova, Viktorija Perepjolkina, Velga Sudraba, Kristīne Mārtinsone, Ainārs Stepens   +4 more
doaj   +1 more source

Personality, Cortisol, and Cognition in Non-demented Elderly Subjects: Results from a Population-Based Study. [PDF]

, 2017
Certain personality traits, in particular higher neuroticism, have been associated, on one hand, with elevated cortisol levels, and on the other hand, with poorer cognitive performance.
Castelao, E., Ouanes, S., Popp, J., Preisig, M., Vidal, P.M., von Gunten, A.   +5 more
core   +2 more sources

Muscle Function: A Personal View [PDF]

Journal of Experimental Biology, 1985
ABSTRACT We are far more likely to arrive at our destination if we know what it is. For those of us who are interested in how muscles work, the destination is the progressive unification of our knowledge of the physics, chemistry and structure - at all levels - of muscular systems.
openaire   +2 more sources