Results 41 to 50 of about 118,388 (311)

Review of the self-sacrifice dimension of the dimensional clinical personality inventory

open access: yesPsicologia: Reflexão e Crítica, 2016
The present study aimed to review the Self-sacrifice scale from the Dimensional Clinical Personality Inventory (IDCP), and investigate its psychometric properties. To this end, the study comprised 199 participants, aging between 18 and 54 years (M= 26.37;
Lucas de Francisco Carvalho   +1 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Men are from Mars, women are from Venus: Exploring gender differences in personality in the South African context

open access: yesSA Journal of Human Resource Management, 2013
Orientation: Gender differences in personality have been explored in American and European contexts, but African and specifically South African research in the area is lacking.
Sumaya Laher, Sarah Croxford
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Personification of ChatGPT (GPT-4)—Understanding Its Personality and Adaptability

open access: yesInformation
Thanks to the publication of ChatGPT, Artificial Intelligence is now basically accessible and usable to all internet users. The technology behind it can be used in many chatbots, whereby the chatbots should be trained for the respective area of ...
Leandro Stöckli   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Personality Traits and Fibromyalgia Syndrome

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022
Background and Objective: Fibromyalgia syndrome (FMS) is considered as a widespread chronic pain disorder of unknown etiology. Since personality traits can play an important role in the development of FMS, this review article was conducted in order to ...
M Vesal, K Asgari, H Roohafza, P Adibi
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The Personality of the Intelligent Cockpit? Exploring the Personality Traits of In-Vehicle LLMs with Psychometrics

open access: yesInformation
The development of large language models (LLMs) has promoted a transformation of human–computer interaction (HCI) models and has attracted the attention of scholars to the evaluation of personality traits of LLMs.
Qianli Lin, Zhipeng Hu, Jun Ma
doaj   +1 more source

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