Results 151 to 160 of about 552,474 (393)

Persons, post-persons and thresholds [PDF]

open access: yesJournal of Medical Ethics, 2011
DeGrazia argues that post-persons have as much justification in believing that they have higher moral status than persons as persons have in believing that they have higher moral status than animals. DeGrazia's claim presupposes that what Buchanan calls the “moral equality assumption” is false.
openaire   +4 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Occluded Person Re-identification [PDF]

open access: yesarXiv, 2018
Person re-identification (re-id) suffers from a serious occlusion problem when applied to crowded public places. In this paper, we propose to retrieve a full-body person image by using a person image with occlusions. This differs significantly from the conventional person re-id problem where it is assumed that person images are detected without any ...
arxiv  

It's Not a Matter of Time: Highlights From the 2011 Competency-Based Learning Summit [PDF]

open access: yes, 2011
Outlines discussions about the potential and challenges of competency-based learning in transforming the current time-based system, including issues of accountability, equity, personalization, and aligning policy and practice.
Chris Sturgis   +2 more
core  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

How Personal is Machine Learning Personalization? [PDF]

open access: yesarXiv, 2019
Though used extensively, the concept and process of machine learning (ML) personalization have generally received little attention from academics, practitioners, and the general public. We describe the ML approach as relying on the metaphor of the person as a feature vector and contrast this with humanistic views of the person.
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Revealing Personality Traits: A New Benchmark Dataset for Explainable Personality Recognition on Dialogues [PDF]

open access: yesarXiv
Personality recognition aims to identify the personality traits implied in user data such as dialogues and social media posts. Current research predominantly treats personality recognition as a classification task, failing to reveal the supporting evidence for the recognized personality.
arxiv  

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