Results 161 to 170 of about 552,474 (393)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Personalization of the Microbiota of Donor Human Milk with Mother’s Own Milk

open access: yesFrontiers in Microbiology, 2017
The American Academy of Pediatrics recommends that extremely preterm infants receive mother’s own milk (MOM) when available or pasteurized donor breast milk (DBM) when MOM is unavailable.
Nicole T. Cacho   +9 more
doaj   +1 more source

Would You Like to Be a Prosumer? Information Revelation, Personalization and Price Discrimination in Electronic Markets [PDF]

open access: yes
Electronic commerce and flexible manufacturing allow personalization of initially standardized products at low cost. Will customers provide the information necessary for personalization?
Karl Morasch, Martin Bandulet
core  

Personalized information systems : personalization, implementation levels a conceptual framework [PDF]

open access: yes, 2012
Personalized Information Systems (also named Personal Applications – PA) are software applications that exhibit personalized features, adjusted to the preferences or user’s needs. PA can provide benefits related to customer relationship or related to the
Carvalho, João Álvaro   +1 more
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

PERCEIVED SERVICE QUALITY IN CONTEXT OF RURAL AND URBAN BANKS IN PAKISTAN [PDF]

open access: yesParadigms, 2016
Perceived service quality is very important concept in banking sector. It is therefore necessary to acknowledge the perception of customers from different areas-as they are becoming more critical and demanding.
MUHAMMAD FAROOQ SHABBIR   +4 more
doaj  

From Great Men to Ordinary Citizens? The Biographical Approach to Narrating European Integration in Museums

open access: yesCulture Unbound: Journal of Current Cultural Research, 2011
The history of European integration is not easy to tell – in books or, for that matter, in museums. Most importantly, it appears to lack drama. This lack of drama creates a dilemma for museum practitioners who wish to tell stories about the contemporary ...
Wolfram Kaiser
doaj   +1 more source

MFP-VTON: Enhancing Mask-Free Person-to-Person Virtual Try-On via Diffusion Transformer [PDF]

open access: yesarXiv
The garment-to-person virtual try-on (VTON) task, which aims to generate fitting images of a person wearing a reference garment, has made significant strides. However, obtaining a standard garment is often more challenging than using the garment already worn by the person. To improve ease of use, we propose MFP-VTON, a Mask-Free framework for Person-to-
arxiv  

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