Results 81 to 90 of about 50,358 (223)

If it does not help, it might hurt: Pharmacodynamics of a second IVIg course in Guillain–Barré syndrome

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives Intravenous immunoglobulin (IVIg) is an effective treatment for Guillain–Barré syndrome (GBS), but recovery varies between patients. This study aims to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of a single and a second IVIg dose (SID) in patients with GBS.
Sander J. van Tilburg, Ruth Huizinga, Krista Kuitwaard, Sebastiaan D.T. Sassen, Christa Walgaard, Pieter A. van Doorn, Bart C. Jacobs, Birgit C.P Koch   +7 more
wiley   +1 more source

Cerebral autoregulation in patients with acute lacunar infarction: a reliable predictor of outcome

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective To further investigate the association between dynamic cerebral autoregulation (dCA) and the outcomes in patients with acute lacunar infarction. Methods Patients were prospectively and consecutively enrolled at The First Hospital of Jilin University between 2016 and 2023. dCA was monitored at 1–3 and 7–10 days after the stroke.
Xiang‐Kun Si, Song Xue, Xin Zhou, Ya‐Nan Guo, Wen‐Yu Du, Yang Qu, Xin Sun, Zhen‐Ni Guo   +7 more
wiley   +1 more source

Dynamic Generation of Personalities with Large Language Models [PDF]

arXiv
In the realm of mimicking human deliberation, large language models (LLMs) show promising performance, thereby amplifying the importance of this research area. Deliberation is influenced by both logic and personality. However, previous studies predominantly focused on the logic of LLMs, neglecting the exploration of personality aspects.
arxiv  

The burden of intracranial atherosclerosis on cerebral small vessel disease: A community cohort study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah, Heng Du, Wenjie Yang, Huixing Zeng, Jason Tsz Lok Chan, Michael Lung Cheung Lo, Xiangyan Chen   +6 more
wiley   +1 more source

Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi, Zitian Tang, Wendy Dong, Jenna Ulibarri, Elvisa Mehinovic, Simone Thomas, Ahmet Höke, Sheng Chih Jin   +7 more
wiley   +1 more source

Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan, Huaju Tian, Cheng Wu, Yue Zhao, Daiying Zhang, Yujie Zheng, Yuan Li, Xiaoxia Duan   +7 more
wiley   +1 more source

Persons and Personality [PDF]

Journal of Medical Ethics, 1988
openaire   +2 more sources

Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan, Shravni Deshmukh, Mark Cummings, Aditi Doshi, Kourosh Rezania, Sally Freels, Gina Sawa   +6 more
wiley   +1 more source

Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia ...
Zhu Guan‐Yu, Yin Zi‐Xiao, Chen Ying‐Chuan, Timon Merk, Thomas Binns, Ma Ruo‐Yu, Du Ting‐Ting, Liu Yu‐Ye, Xie Hu‐Tao, Shi Lin, Yang An‐Chao, Meng Fan‐Gang, Wolf‐Julian Neumann, Andrea A. Kühn, Zhang Jian‐Guo   +14 more
wiley   +1 more source

Association of Changes in Hand Pain With BMI, Employment, and Mental Well‐Being Over Four Years in Patients With Hand Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to characterize patients with hand osteoarthritis (OA) with deteriorating or improving hand pain and to investigate patients achieving good clinical outcome after four years. Methods We used four‐year annual Australian/Canadian Hand Osteoarthritis Index (AUSCAN) pain subscale (range 0–20) measurements from the Hand OSTeoArthritis in ...
Coen van der Meulen, Lotte A. van de Stadt, Saskia J. Buck, Frits R. Rosendaal, Sietse E. S. Terpstra, Margreet Kloppenburg   +5 more
wiley   +1 more source