Results 21 to 30 of about 627,364 (295)

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans

Communications Biology, 2022
A genome-wide association study in a Chinese population identifies SNPs associated with serum copper levels. Mendelian randomization analysis reveals causal effects on multiple human phenotypes in East Asian and European populations.
Wenjun Yang, Longman Li, Xiuming Feng, Hong Cheng, Xiaoting Ge, Yu Bao, Lulu Huang, Fei Wang, Chaoqun Liu, Xing Chen, Zengnan Mo, Xiaobo Yang   +11 more
doaj   +1 more source

Pharmacogenetics and personalized medicine

Saúde & Tecnologia, 2016
Pharmacogenetics aims to identify genetic differences between individuals that may influence the response to drug therapy, improving their effectiveness and safety. Associated with the pharmacogenetics emerges ‘personalized medicine’.
Miguel Brito
doaj   +1 more source

Stroke genetics: prospects for personalized medicine. [PDF]

, 2012
Epidemiologic evidence supports a genetic predisposition to stroke. Recent advances, primarily using the genome-wide association study approach, are transforming what we know about the genetics of multifactorial stroke, and are identifying novel stroke ...
A Gschwendtner, A Hassan, A Helgadottir, A Helgadottir, A Joutel, A Viswanathan, AB Singleton, AJ Bowes, AV Shirodkar, B Rohrer, C Bellenguez, CAPRIE Steering Committee, CS Ku, D Sibbing, DF Gudbjartsson, DJ Klionsky, DK Wysowski, DL Bhatt, DR Holmes Jr, DS Budnitz, E Flossmann, G Paré, HC Diener, HS Markus, HS Markus, Hugh S Markus, J Hardy, JA Johnson, JB Olesen, JF Meschia, JL Mega, JN Hirschhorn, JT O'Brien, L Wang, M Dichgans, M Kubo, M Serizawa, MA Ikram, MV Holmes, P Jerrard-Dunne, P Kraft, P Polychronopoulos, PC Ng, RL Sacco, RS Epstein, S Bevan, S Gretarsdottir, S Gretarsdottir, S Lanfranconi, S Olsson, S Seshadri, S Seshadri, SE Nissen, The International Warfarin Pharmacogenetics Consortium, VG Manolopoulos, VL Roger   +55 more
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Intelligent techniques using molecular data analysis in leukaemia: an opportunity for personalized medicine support system [PDF]

, 2017
The use of intelligent techniques in medicine has brought a ray of hope in terms of treating leukaemia patients. Personalized treatment uses patient’s genetic profile to select a mode of treatment.
Adelson, D., Banjar, H., Brown, A., Chaudhri, N.   +3 more
core   +3 more sources

Personalized Medicine in Allergy [PDF]

Allergy, Asthma & Immunology Research, 2017
Allergic disease is among the most common pathologies worldwide and its prevalence has constantly increased up to the present days, even if according to the most recent data it seems to be slightly slowing down. Allergic disease has not only a high rate of misdiagnosis and therapeutic inefficacy, but represents an enormous, resource-absorbing black ...
Ferrando, Matteo, Bagnasco, Diego, Varricchi, Gilda, Bernardi, Stefano, BRAGANTINI, ALICE, PASSALACQUA, GIOVANNI, CANONICA, GIORGIO   +6 more
openaire   +5 more sources

Personalized medicine in rheumatology

Rheumatology, 2016
In the era of the 21st century, rheumatoid arthritis (RA) is still poorly characterized. Rheumatoid arthritis is a common but heterogeneous disease, not only in the course and clinical symptoms, but also in the clinical response to treatment. Now it is
Anna Kłak, Agnieszka Paradowska-Gorycka, Brygida Kwiatkowska, Filip Raciborski   +3 more
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DDIAS, DNA damage-induced apoptosis suppressor, is a potential therapeutic target in cancer

Experimental and Molecular Medicine, 2023
Increasing evidence indicates that DNA damage-induced apoptosis suppressor (DDIAS) is an oncogenic protein that is highly expressed in a variety of cancers, including colorectal cancer, lung cancer, breast cancer, and hepatocellular carcinoma (HCC).
Joo-Young Im, Mi-Jung Kang, Bo-Kyung Kim, Misun Won   +3 more
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Transcriptomic Analysis of Gene Networks Regulated by U11 Small Nuclear RNA in Bladder Cancer

Frontiers in Genetics, 2021
Small nuclear RNA is a class of non-coding RNA that widely exist in the nucleus of eukaryotes. Accumulated evidences have shown that small nuclear RNAs are associated with the regulation of gene expression in various tumor types.
Zhenxing Wang, Zhenxing Wang, Zhenxing Wang, Xi Wang, Xi Wang, Yaobang Wang, Yaobang Wang, Shaomei Tang, Chao Feng, Chao Feng, Lixin Pan, Lixin Pan, Qinchen Lu, Qinchen Lu, Yuting Tao, Yuting Tao, Yuanliang Xie, Yuanliang Xie, Yuanliang Xie, Qiuyan Wang, Qiuyan Wang, Zhong Tang, Zhong Tang, Zhong Tang   +23 more
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Beyond Personalized Medicine [PDF]

Personalized Medicine, 2009
hope [1]. The aim of this article is to illustrate the path of pharmacogenomics through Seige’s cycle, from euphoria to disappointment. On this basis, I argue for the necessity of a more holistic view of individualized medicine without equating it to pharmacogenomics.
openaire   +3 more sources

The myeloid sarcoma treated by Venetoclax with hypomethylating agent followed by stem cell transplantation: rare case report

BMC Women's Health, 2021
Background Myeloid sarcoma (MS) is a very rare condition, develops both in patients with other hematological neoplasms, and as isolated tumor. MS of the gynecologic tract is extremely rare.
Aleksina Shatilova, Larisa Girshova, Daniil Zaytsev, Irina Budaeva, Yuliya Mirolyubova, Darya Ryzhkova, Roman Grozov, Konstantin Bogdanov, Tatiana Nikulina, Dmitriy Motorin, Darina Zammoeva, Svetlana Efremova, Vladimir Ivanov, Alexey Petukhov, Yuliya Alekseeva, Andrey Zaritskey   +15 more
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