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Personalized medicine in internal medicine
Personalized medicine - a new direction in medicine, which is based on the study of various biomarkers and the use of new methods of molecular analysis (primarily evaluating the activity of isoenzymes of cytochrome P450), allowing individualized approach to the selection of both the drugs and the selection of the dosing regimen for the purpose of ...
V G, Kukes +12 more
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Ethics, evidence and economics in the pursuit of “personalized medicine” [PDF]
: Despite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today,
Wendy Lipworth +7 more
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Application of Patient-Derived Cancer Organoids to Personalized Medicine
Cell models are indispensable for the research and development of cancer therapies. Cancer medications have evolved with the establishment of various cell models.
Furukawa, Toru +3 more
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Personalized Medicine in Kidney Disease
The Special Issue “Personalized Medicine in Kidney Disease” is focused on the importance of customized medicine in nephrology as it represents one of the main characteristics of successful therapeutic results [...
Rossella Siligato +2 more
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DDIAS, DNA damage-induced apoptosis suppressor, is a potential therapeutic target in cancer
Increasing evidence indicates that DNA damage-induced apoptosis suppressor (DDIAS) is an oncogenic protein that is highly expressed in a variety of cancers, including colorectal cancer, lung cancer, breast cancer, and hepatocellular carcinoma (HCC).
Joo-Young Im +3 more
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Transcriptomic Analysis of Gene Networks Regulated by U11 Small Nuclear RNA in Bladder Cancer
Small nuclear RNA is a class of non-coding RNA that widely exist in the nucleus of eukaryotes. Accumulated evidences have shown that small nuclear RNAs are associated with the regulation of gene expression in various tumor types.
Zhenxing Wang +23 more
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The Case for Personalized Medicine [PDF]
Personalized medicine may be considered an extension of traditional approaches to understanding and treating disease, but with greater precision. Physicians may now use a patient's genetic variation or expression profile as well as protein and metabolic markers to guide the selection of certain drugs or treatments.
Edward, Abrahams, Mike, Silver
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The Promise of Nanotechnology in Personalized Medicine
Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine is an application of the advances of nanotechnology in medicine and is being integrated into diagnostic and therapeutic tools to manage an array of medical conditions ...
Khaled Greish +11 more
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Pharmacogenetics and personalized medicine
Pharmacogenetics aims to identify genetic differences between individuals that may influence the response to drug therapy, improving their effectiveness and safety. Associated with the pharmacogenetics emerges ‘personalized medicine’.
Miguel Brito
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Background Identifying biomarkers related to the diagnosis and treatment of gastric cancer (GC) has not made significant progress due to the heterogeneity of tumors.
Bo-Kyung Kim +16 more
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